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Nuclear Receptor Mutation Database |
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Disclaimer
Bugs or remarks should be reported to this address
Some tips on how to use the query system:
- Keyword search: Keywords should be separated by a space. Don't use quote characters, since they will be automatically removed.
Use the "OR" or "AND" radiobuttons to choose the operator. The search is case sensitive.
- All fields are interconnected by AND statements, eg. "Homo sapiens" AND "NGFIB".
- WITHIN the first 4 fields, you can make multiple selections which are then connected by an OR statement, eg. "OMIM" OR "SwissProt".
- POSITION/REGION specific searching: For information about the 3D alignment numbering scheme and Helix/Sheet definitions, check out the alignment.
- The Helix and Sheet regions in the REGION field concern only the Ligand Binding Domain (LBD).
- You can look for nonsense mutations (TER or X) by selecting 'TER' in the 'To' menu. You cannot select 'TER' in the 'From' menu.
- The results page: the Swissprot code links to the Swissprot file, the receptor code links to the NucleaRDB entry.
- Sometimes a mutant is annotated with (v) or (m). (v) indicates a natural variant (polymorphism), (m) indicates an experimental mutagen.
- If the mutation doesn't come from SwissProt, the link to the source will also be shown.
FEBRUARY 2005:
Currently the database holds 1704 entries
The mutations in the database derive from SwissProt, NucleaRDB, OMIM, VDR page, PNR page, GRR Page and articles searching.
Some statistics on the current database content can be found here.
Made with Postgres and Python - J. Van Durme - 2002-2005 - Contact me