PrionDB: Point mutations extracted from the literature - PRIO_CRIGR

2005, PrionDB.

This data was extracted from medline abstracts and full text papers (when available) in an automated manner.

Each point mutation is linked to the entry specific to the residue position. Citations are linked to the list of point mutations found in the corresponding articles. The last column allows you to go back to the original text via Medline.

Protein	PRIO_CRIGR (PRNP)	Swiss-Prot Cross-reference table Family page
Family alignments	Mammalian prion proteins Prion proteins (PRP, PRNP)

Mutation Location General numbering Reference
P102L Not determined Holscher C et al., J Virol 1998 Medline

D147N Not determined DeMarco ML et al., Proc Natl Acad Sci U S A 2004 Medline

D178N Not determined Fioriti L et al., J Biol Chem 2005 Medline

V210I Not determined Mastrangelo P et al., Gene 2001 Medline

Q217R Not determined Fioriti L et al., J Biol Chem 2005 Medline

Q219K Not determined Mastrangelo P et al., Gene 2001 Medline

Mutation	Location	Reference
P102L	Not determined	Holscher C et al., J Virol 1998	Medline
D147N	Not determined	DeMarco ML et al., Proc Natl Acad Sci U S A 2004	Medline
D178N	Not determined	Fioriti L et al., J Biol Chem 2005	Medline
V210I	Not determined	Mastrangelo P et al., Gene 2001	Medline
Q217R	Not determined	Fioriti L et al., J Biol Chem 2005	Medline
Q219K	Not determined	Mastrangelo P et al., Gene 2001	Medline

F.Horn (priondbcmbi.ru.nl), 22-Aug-2005