This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation D147N was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|General numbering (PrionDB):||-|
|Other point mutations / same protein||List of mutations in PRIO_HUMAN|
Mammalian prion proteins|
Prion proteins (PRP, PRNP)
|Other point mutations / same position||
Position 147 in Mammalian prion proteins family |
Position 147 in Prion proteins (PRP, PRNP) family
|Reference:||The role of electrostatic interaction in triggering the unraveling of stable helix 1 in normal prion protein. A molecular dynamics simulation investigation.|
Ji HF, Zhang HY, Shen L
J Biomol Struct Dyn 2005 Apr;22(5):563-70.
|Other point mutations / same article||List|
|Validation status||Not yet checked|