2005, PrionDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation D178N was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | D178N | |
| Domain: | Not determined | |
| General numbering (PrionDB): | - | |
| Protein: | PRIO_HUMAN (PRNP) | Swiss-Prot Cross-reference table Family page |
| Other point mutations / same protein / same position | Point mutations at position 178 in PRIO_HUMAN | |
| Other point mutations / same protein | List of mutations in PRIO_HUMAN | |
| Family alignments |
Mammalian prion proteins Prion proteins (PRP, PRNP) | |
| Other point mutations / same position |
Position 178 in Mammalian prion proteins family Position 178 in Prion proteins (PRP, PRNP) family | |
| Reference: | Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Pocchiari M, Puopolo M, Croes EA, Budka H, Gelpi E, Collins S, Lewis V, Sutcliffe T, Guilivi A, Delasnerie-Laupretre N, Brandel JP, Alperovitch A, Zerr I, Poser S, Kretzschmar HA, Ladogana A, Rietvald I, Mitrova E, Martinez-Martin P, de Pedro-Cuesta J, Glatzel M, Aguzzi A, Cooper S, Mackenzie J, van Duijn CM, Will RG Brain 2004 Oct;127(Pt 10):2348-59. Epub 2004 Sep 10. | Medline |
| Other point mutations / same article | List | |
| Text source | HTML full text | |
| Validation status | Not yet checked |
Relevant sentences:
D178N
cmbi.ru.nl), 22-Aug-2005