This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation Y218W was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|General numbering (PrionDB):||-|
|Other point mutations / same protein / same position||Point mutations at position 218 in PRIO_HUMAN|
|Other point mutations / same protein||List of mutations in PRIO_HUMAN|
Mammalian prion proteins|
Prion proteins (PRP, PRNP)
|Other point mutations / same position||
Position 218 in Mammalian prion proteins family |
Position 218 in Prion proteins (PRP, PRNP) family
|Reference:||The effect of disease-associated mutations on the folding pathway of human prion protein.|
Apetri AC, Surewicz K, Surewicz WK
J Biol Chem 2004 Apr 23;279(17):18008-14. Epub 2004 Feb 2.
|Other point mutations / same article||List|
|Text source||HTML full text|
|Validation status||True positive|