This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation A117V was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|General numbering (PrionDB):||-|
|Other point mutations / same protein / same position||Point mutations at position 117 in PRIO_MOUSE|
|Other point mutations / same protein||List of mutations in PRIO_MOUSE|
Mammalian prion proteins|
Prion proteins (PRP, PRNP)
|Other point mutations / same position||
Position 118 in Mammalian prion proteins family |
Position 118 in Prion proteins (PRP, PRNP) family
|Reference:||Post-translational import of the prion protein into the endoplasmic reticulum interferes with cell viability: a critical role for the putative transmembrane domain.|
Heller U, Winklhofer KF, Heske J, Reintjes A, Tatzelt J
J Biol Chem 2003 Sep 19;278(38):36139-47. Epub 2003 Jul 8.
|Other point mutations / same article||List|
|Text source||HTML full text|
|Validation status||True positive|