This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation E200K was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|Cited point mutation:||Glu200Lys,Glu-200-Lys|
|General numbering (PrionDB):||-|
|Other point mutations / same protein / same position||Point mutations at position 200 in PRIO_HUMAN|
|Other point mutations / same protein||List of mutations in PRIO_HUMAN|
Mammalian prion proteins|
Prion proteins (PRP, PRNP)
|Other point mutations / same position||
Position 200 in Mammalian prion proteins family |
Position 200 in Prion proteins (PRP, PRNP) family
|Reference:||The Val-210-Ile pathogenic Creutzfeldt-Jakob disease mutation increases both the helical and aggregation propensities of a sequence corresponding to helix-3 of PrP(C).|
Thompson AJ, Barnham KJ, Norton RS, Barrow CJ
Biochim Biophys Acta 2001 Jan 12;1544(1-2):242-54.
|Other point mutations / same article||List|
|Text source||HTML full text|
|Validation status||Not yet checked|