2005, PrionDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation T198 was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | T198 | |
| Cited point mutation: | T199,Thr199 | |
| Domain: | Not determined | |
| General numbering (PrionDB): | - | |
| Protein: | PRIO_MOUSE (Prnp,Prn-p) | Swiss-Prot Cross-reference table Family page |
| Other point mutations / same protein / same position | Point mutations at position 198 in PRIO_MOUSE | |
| Other point mutations / same protein | List of mutations in PRIO_MOUSE | |
| Family alignments |
Mammalian prion proteins Prion proteins (PRP, PRNP) | |
| Other point mutations / same position |
Position 199 in Mammalian prion proteins family Position 199 in Prion proteins (PRP, PRNP) family | |
| Reference: | Role of the helix capping in the stability of the mouse prion (180-213) segment: investigation through molecular dynamics simulations. Iovino M, Falconi M, Petruzzelli R, Desideri A J Biomol Struct Dyn 2001 Oct;19(2):237-46. | Medline |
| Other point mutations / same article | List | |
| Text source | abstract | |
| Validation status | True positive |
Relevant sentences:
Thr199
cmbi.ru.nl), 22-Aug-2005