2005, PrionDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation D178N was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | D178N | |
| Domain: | Not determined | |
| General numbering (PrionDB): | - | |
| Protein: | PRIO_RAT (Prnp,Prn) | Swiss-Prot Cross-reference table Family page |
| Other point mutations / same protein | List of mutations in PRIO_RAT | |
| Family alignments |
Mammalian prion proteins Prion proteins (PRP, PRNP) | |
| Other point mutations / same position |
Position 178 in Mammalian prion proteins family Position 178 in Prion proteins (PRP, PRNP) family | |
| Reference: | Influence of mutations associated with familial prion-related encephalopathies on biological activity of prion protein peptides. Forloni G, Angeretti N, Malesani P, Peressini E, Rodriguez Martin T, Della Torre P, Salmona M Ann Neurol 1999 Apr;45(4):489-94. | Medline |
| Other point mutations / same article | List | |
| Text source | abstract | |
| Validation status | True positive |
Relevant sentences:
D178N
cmbi.ru.nl), 22-Aug-2005