This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation A117V was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|General numbering (PrionDB):||-|
|Other point mutations / same protein||List of mutations in PRIO_RAT|
Mammalian prion proteins|
Prion proteins (PRP, PRNP)
|Other point mutations / same position||
Position 117 in Mammalian prion proteins family |
Position 117 in Prion proteins (PRP, PRNP) family
|Reference:||Influence of mutations associated with familial prion-related encephalopathies on biological activity of prion protein peptides.|
Forloni G, Angeretti N, Malesani P, Peressini E, Rodriguez Martin T, Della Torre P, Salmona M
Ann Neurol 1999 Apr;45(4):489-94.
|Other point mutations / same article||List|
|Validation status||True positive|