This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation L108F was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|Cited point mutation:||L109F,Leu109Phe|
|General numbering (PrionDB):||-|
|Other point mutations / same protein / same position||Point mutations at position 108 in PRIO_MOUSE|
|Other point mutations / same protein||List of mutations in PRIO_MOUSE|
Mammalian prion proteins|
Prion proteins (PRP, PRNP)
|Other point mutations / same position||
Position 109 in Mammalian prion proteins family |
Position 109 in Prion proteins (PRP, PRNP) family
|Reference:||Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein.|
Liemann S, Glockshuber R
Biochemistry 1999 Mar 16;38(11):3258-67.
|Other point mutations / same article||List|
|Text source||HTML and PDF full texts|
|Validation status||True positive|