NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       Q9U1U2_CAEEL
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      CEY69H2_10
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 854.24 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

Q9U1U2_CAEEL       1 MSSDLPAAPSDLPSTSSNLLCTVCGAPASGRRYGAAAACLACIVFFRRS 
                     MSSDLPAAPSDLPSTSSNLLCTVCGAPASGRRYGAAAACLACIVFFRRS 
                     MSSDLPAAPSDLPSTSSNLLCTVCGAPASGRRYGAAAACLACIVFFRRS 
CEY69H2_10         1 attgccggctgcctattacctagtggcgagactgggggtcgtagttcct 
                     tccatcccccatcccccattgctggcccggggagccccgtcgttttggc 
                     gacttatgacttccaacctccaccttacctgacaccccctccccccgaa 


Q9U1U2_CAEEL      50 VLRKIHYTCQALGRCEITVASRCVCRYCRMQKCLAAGMDPRAIQIRDLL 
                     VLRKIHYTCQALGRCEITVASRCVCRYCRMQKCLAAGMDPRAIQIRDLL 
                     VLRKIHYTCQALGRCEITVASRCVCRYCRMQKCLAAGMDPRAIQIRDLL 
CEY69H2_10       148 gcaaactatcgcgatgaaggtctgtcttaacattgggagccgacacgcc 
                     ttgataacgactgggatctccggtggaggtaagtccgtacgctatgatt 
                     caagcccctgaacgtgttaatattcgctaggacggtggtttaaacgctt 


Q9U1U2_CAEEL      99 GPRSLSSRLSSRRNLDFSPILDLTDFLSLQRTQCSSGNQKCFQQTSREA 
                     GPRSLSSRLSSRRNLDFSPILDLTDFLSLQRTQCSSGNQKCFQQTSREA 
                     GPRSLSSRLSSRRNLDFSPILDLTDFLSLQRTQCSSGNQKCFQQTSREA 
CEY69H2_10       295 gcaatttatttccacgttcatgtagtcaccaactatgacattccatagg 
                     gcggtccgtccggatatccttatcattgtagcaggcgaaagtaaccgac 
                     gagcagaaacatgtatttgtgcatttgcaagcgcctacaatcgattaaa 


Q9U1U2_CAEEL     148 TSSDINSSLKLAIEHANSWALKFNFYENFTEKTSILSEFAIGFMLIDQA 
                     TSSDINSSLKLAIEHANSWALKFNFYENFTEKTSILSEFAIGFMLIDQA 
                     TSSDINSSLKLAIEHANSWALKFNFYENFTEKTSILSEFAIGFMLIDQA 
CEY69H2_10       442 attgaattcacgagcgattgcatattgatagaatattgtgagtacagcg 
                     cccatacctatctaacacgctatataaatcaaccttcatctgttttaac 
                     ctccacataaaccgtatagtgattttatcgaatatagatccatgactga 


Q9U1U2_CAEEL     197 FKTAEEAENGFWLLQNGTFLVENEHKSYSKYVSEILNSIAVPFKNLKIE 
                     FKTAEEAENGFWLLQNGTFLVENEHKSYSKYVSEILNSIAVPFKNLKIE 
                     FKTAEEAENGFWLLQNGTFLVENEHKSYSKYVSEILNSIAVPFKNLKIE 
CEY69H2_10       589 taagggggagttcccagattggagcatttatgtgacataggctaacaag 
                     taccaacaagtgttaagctttaaaaacacaatcattactctctaatata 
                     catgaatatccgcgatgttgcatgcaccaatgtaaccaaatgcatgata 


Q9U1U2_CAEEL     246 EFECVILKILLFLSGGCRKIFKFWENPLKFSANSLQNHRDLAPHRKYCF 
                     EFECVILKILLFLSGGCRKIFKFWENPLKFSANSLQNHRDLAPHRKYCF 
                     EFECVILKILLFLSGGCRKIFKFWENPLKFSANSLQNHRDLAPHRKYCF 
CEY69H2_10       736 gtgtgataatctttggtcaatattgactattgatccacagcgcccattt 
                     atagtttatttttcggggattatgaactatccactaaagatccagaagt 
                     gtgcgtgatggtgatgcaattatgattaatactcgatcgttttccgttc 


Q9U1U2_CAEEL     295 KLLTEHRSPPEAGEIILLLSSIRCVIKSFYNVTRISDIFNVENFDDDVK 
                     KLLTEHRSPPEAGEIILLLSSIRCVIKSFYNVTRISDIFNVENFDDDVK 
                     KLLTEHRSPPEAGEIILLLSSIRCVIKSFYNVTRISDIFNVENFDDDVK 
CEY69H2_10       883 accagccaccggggaatccataatgaatttagaaatgataggatgggga 
                     attcaaggccacgatttttgctggttactaatcgtcattataataaata 
                     ggcggcgctaacgaatagccatgtcagatttataattttttattcctta 


Q9U1U2_CAEEL     344 VVLVE                                             
                     VVLVE                                             
                     VVLVE                                             
CEY69H2_10      1030 ggcgg                                             
                     tttta                                             
                     tatta                                             


//


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005