NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       Q8MXE5_CAEEL
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      AF100669_11
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 622.96 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

Q8MXE5_CAEEL       1 MRFNPCDVCLSPGNGKHFGVDACRGCTAFFRRTIVNKRNYSCSEDDTCE 
                     MRFNPCDVCLSPGNGKHFGVDACRGCTAFFRRTIVNKRNYSCSEDDTCE 
                     MRFNPCDVCLSPGNGKHFGVDACRGCTAFFRRTIVNKRNYSCSEDDTCE 
AF100669_11        1 actactggtctcgagactggggtagtagttccaagaaaatatagggatg 
                     tgtacgatgtccgagaatgtacggggccttggcttaagaagggaaacga 
                     gtctgttattgtatagtttcttcatcaaccgaaaccgacctttatctta 


Q8MXE5_CAEEL      50 IEKSEGLLCKKCRFEKCLKVGMKKESIQKHRDIYGRRNPENRALIISPS 
                     IEKSEGLLCKKCRFEKCLKVGMKKESIQKHRDIYGRRNPENRALIISPS 
                     IEKSEGLLCKKCRFEKCLKVGMKKESIQKHRDIYGRRNPENRALIISPS 
AF100669_11      148 agatggcctaatctgattaggaaagtacaccgatgccacgacgcaatct 
                     taacagttgaaggtaagtatgtaaactaaagatagggacaagctttccc 
                     taaaagatcgacataatgatagaaagtagttctttcacgatatgattga 


Q8MXE5_CAEEL      99 TSQLQVTIPITLLSSVKRNYAELENVREIVHRMDGFSMFLKPAPRGQTY 
                     TSQLQVTIPITLLSSVKRNYAELENVREIVHRMDGFSMFLKPAPRGQTY 
                     TSQLQVTIPITLLSSVKRNYAELENVREIVHRMDGFSMFLKPAPRGQTY 
AF100669_11      295 atcccgaacaacttagaaatggtgagagagcaaggtaatcacgccgcat 
                     ccatatctctcttcgtagaacataatgattagtagtgtttacccggaca 
                     tagtacatctcaaattgatcaagataaatacagttctgtggatattaat 


Q8MXE5_CAEEL     148 KETYRLLLREFYLVSDWVSNCFPLFKELPNSQKDILLRNFYLTFYNLEA 
                     KETYRLLLREFYLVSDWVSNCFPLFKELPNSQKDILLRNFYLTFYNLEA 
                     KETYRLLLREFYLVSDWVSNCFPLFKELPNSQKDILLRNFYLTFYNLEA 
AF100669_11      442 agatcttccgtttgtgtgtattcctagccatcagacccattcattatgg 
                     aacagtttgatattcagtcagtcttaatcacaaatttgatatctaatac 
                     aagttggcagctagtcgtgtctattaaaattggcatgacccattccgat 


Q8MXE5_CAEEL     197 GFFACQHNKIDVWFLPNGNFIDCQNLEAFYYDPHNQQPMTSADAAR    
                     GFFACQHNKIDVWFLPNGNFIDCQNLEAFYYDPHNQQPMTSADAAR    
                     GFFACQHNKIDVWFLPNGNFIDCQNLEAFYYDPHNQQPMTSADAAR    
AF100669_11      589 gttgtccaaaggtttcagatagtcatggtttgccacccaatgggga    
                     gttcgaaaatatgttcagattagaatactaaacaaaactcccaccg    
                     actgtgttaaccgtactatttttatgattcttactaaagagattag    


//


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005