NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       Q8AVK3_XENLA
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      BC042224_3
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 1135.13 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

Q8AVK3_XENLA       1 MRLSKALIDMDMADYTEALDPAYTTLEFENMQVLSIGTDTSTSDVTSLS 
                     MRLSKALIDMDMADYTEALDPAYTTLEFENMQVLSIGTDTSTSDVTSLS 
                     MRLSKALIDMDMADYTEALDPAYTTLEFENMQVLSIGTDTSTSDVTSLS 
BC042224_3         1 aactagtagagaggtaggtgcgtaacgtgaacgttagagatatggaaca 
                     tgtcacttatatcaacactaccacctataatattctgcaccccatcgtg 
                     gagcatgacgtggttaaagtttcccgatatgatgttatccctatgatct 


Q8AVK3_XENLA      50 ASNSIGINSLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRF 
                     ASNSIGINSLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRF 
                     ASNSIGINSLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRF 
BC042224_3       148 gtaaagaatttgatggagagactggtatggtagttaaagaaacatttat 
                     ccagtgtactgctggagccgaaagccggaggagttgggtgaaatacggt 
                     cactcctctgccttgcagtcactgtccccccgcccggttgaccgcacgc 


Q8AVK3_XENLA      99 SRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDS 
                     SRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDS 
                     SRQCVVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDS 
BC042224_3       295 aactgggagaaactcttccaattaggaaagggcagcgaaaaaatatgga 
                     ggagttaaaagaaggaggtaagtgcgtaaactaaagagtgcggcgaaag 
                     caattgtgcaacgtgccggggtcgtaggaatagtggcgatggggttacc 


Q8AVK3_XENLA     148 SLPSINVLIQAEVLSQQITSSVGVLNTDIRGKKIACIIDVCDSMKQQLL 
                     SLPSINVLIQAEVLSQQITSSVGVLNTDIRGKKIACIIDVCDSMKQQLL 
                     SLPSINVLIQAEVLSQQITSSVGVLNTDIRGKKIACIIDVCDSMKQQLL 
BC042224_3       442 atctaagtacgggctccaattgggtaagaagaaagtaaggtgtaacccc 
                     gtcctatttacattcaatccctgttacatggaatcgttatgactaaatt 
                     tagcttcataaattcagaccatgggcacaacggccccacgttcgagggg 


Q8AVK3_XENLA     197 VLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMFKDILLL 
                     VLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMFKDILLL 
                     VLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMFKDILLL 
BC042224_3       589 gtggtgatacgttgcccggcggctcgcgggctccggaaataatagatcc 
                     tttagcaatcctgatctaaatcttgcacgaatttgccagctttaatttt 
                     cggggagtcgtctatagtcggtgagacagacgttgtaggaggtacagtc 


Q8AVK3_XENLA     246 GNDRLIPRNCPELEVGRVAVRILDELVLPFQELQIDDNEYACLKAIIFF 
                     GNDRLIPRNCPELEVGRVAVRILDELVLPFQELQIDDNEYACLKAIIFF 
                     GNDRLIPRNCPELEVGRVAVRILDELVLPFQELQIDDNEYACLKAIIFF 
BC042224_3       736 gagccaccatcgcgggcgggaacggcgcctcgccaggagtgtcagaatt 
                     gaagttcgagcatatggtctgttaatttctaatataaaaacgtactttt 
                     atcactagttaacagccgagaagtagttccagtgctctacgcgatcatt 


Q8AVK3_XENLA     295 DPDAKGLSDPTKIKRMRYQVQVSLEDYINDRQYDSRGRFGDLLLLLPTL 
                     DPDAKGLSDPTKIKRMRYQVQVSLEDYINDRQYDSRGRFGDLLLLLPTL 
                     DPDAKGLSDPTKIKRMRYQVQVSLEDYINDRQYDSRGRFGDLLLLLPTL 
BC042224_3       883 gcggagtagcaaaaaaatcgcgacggtaagcctgtagatggccctccac 
                     acacagtgaccatagtgaatatgtaaataagaaacgggtgatttttcct 
                     cttcatactacgcgaggcgggccggtcctttgtcaaagtgtctcgctgg 


Q8AVK3_XENLA     344 QSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANEASHTHHHLHPHL 
                     QSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANEASHTHHHLHPHL 
                     QSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANEASHTHHHLHPHL 
BC042224_3      1030 caaatcaagcactgactgagaagacccgaccggtgaggtcaccctcccc 
                     agtcgattaatattattgtcataattaatttggccaaccacaaatacat 
                     gccagggcgacgttgcttgcgtccggaggctgttatatacctctgcgtg 


Q8AVK3_XENLA     393 VQDHLATNVIVANNTLPSQLHNGQMSTPETPQPSPPAGSGAEQYKIVHG 
                     VQDHLATNVIVANNTLPSQLHNGQMSTPETPQPSPPAGSGAEQYKIVHG 
                     VQDHLATNVIVANNTLPSQLHNGQMSTPETPQPSPPAGSGAEQYKIVHG 
BC042224_3      1177 gcgccgaagaggaaacctcccagcatacgaccctccggtgggctaagcg 
                     taaatccatttcaactccataagatcccaccacccccgcgcaaaattag 
                     tattaaacttaccctgacatctaggtaagtcaatattcagaggtataca 


Q8AVK3_XENLA     442 TIASINKQPTSIPQSTITKQEAM                           
                     TIASINKQPTSIPQSTITKQEAM                           
                     TIASINKQPTSIPQSTITKQEAM                           
BC042224_3      1324 aagtaaaccatacctaaaacgga                           
                     ctcctaaaccctcacctcaaact                           
                     ctatccaaacctaagcccagatg                           


//


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005