NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       Q8AUM4_ORENI
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      AY135398_2
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 629.95 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

Q8AUM4_ORENI       1 MDSACRCSTSSDRTSNPILYNILSQMDGSRLSQGNFSYNSVPHRCKCEA 
                     MDSACRCSTSSDRTSNPILYNILSQMDGSRLSQGNFSYNSVPHRCKCEA 
                     MDSACRCSTSSDRTSNPILYNILSQMDGSRLSQGNFSYNSVPHRCKCEA 
AY135398_2         1 agagtcttaaagaatacactaacacaggaacacgatatatgccatatgg 
                     tagcgggccggagccacttaattgatagggtgagatgaactcaggagac 
                     gccgtttaccttgtattcgcccgcagtccagcaccccctagtcacatga 


Q8AUM4_ORENI      50 RRTVCLKRPSEICKEASAVLVKTLNFMKNLPAFNQLPPNDQFALLKSCW 
                     RRTVCLKRPSEICKEASAVLVKTLNFMKNLPAFNQLPPNDQFALLKSCW 
                     RRTVCLKRPSEICKEASAVLVKTLNFMKNLPAFNQLPPNDQFALLKSCW 
AY135398_2       148 ccagttaactgataggtggcgaacataaatcgtaccccagctgccaatt 
                     ggctgtagccatgaaccctttactattaatcctaatccaaatcttaggg 
                     agagcgaggggtcaatggtgaacatcgacgcctcggtaccgcctgaccg 


Q8AUM4_ORENI      99 APLFILGLAQERVDFEVTDIPTDSMLKKILLNRPESPEVEREQPTMAGV 
                     APLFILGLAQERVDFEVTDIPTDSMLKKILLNRPESPEVEREQPTMAGV 
                     APLFILGLAQERVDFEVTDIPTDSMLKKILLNRPESPEVEREQPTMAGV 
AY135398_2       295 gcctacgcgcgcggtggagacagaacaaaccaacgacgggagccaaggg 
                     ccttttgtcaagtatatcatccagttaatttagcagcatagaacctcgt 
                     gacctgtgcagtgccgggccctccggagccgcacgccggagggctgctc 


Q8AUM4_ORENI     148 SKLVSCLKKFWSLDLSPKEYAYLKGTTIFNPDVPDLKAALFVEGLQQEA 
                     SKLVSCLKKFWSLDLSPKEYAYLKGTTIFNPDVPDLKAALFVEGLQQEA 
                     SKLVSCLKKFWSLDLSPKEYAYLKGTTIFNPDVPDLKAALFVEGLQQEA 
AY135398_2       442 aacgttcaattatgtacagtgtcagaaatacggcgtaggctgggtccgg 
                     gattcgtaatggtatgcaaacatagccttacatcatacctttagtaaac 
                     cacgtccagtgtgtgccggcaccagcgattacaatggacgtgacgagat 


Q8AUM4_ORENI     197 QQALSKVVQLLHPGDGDRFARILLTASMLQSITPSLITELFFRPVIGQA 
                     QQALSKVVQLLHPGDGDRFARILLTASMLQSITPSLITELFFRPVIGQA 
                     QQALSKVVQLLHPGDGDRFARILLTASMLQSITPSLITELFFRPVIGQA 
AY135398_2       589 ccgtaaggcccccggggctgcaccagtaccaaacacaagcttccgagcg 
                     aactgattattacgagagtcgtttcccttagtccgttcatttgcttgac 
                     ggcacggtgcccggcgccttacccaccgggccccccctacccgtgaagg 


Q8AUM4_ORENI     246 NLLELLVDMLFCR                                     
                     NLLELLVDMLFCR                                     
                     NLLELLVDMLFCR                                     
AY135398_2       736 accgccggactta                                     
                     attatttatttgg                                     
                     cgggggccgccca                                     


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005