NucleaRDB: Pairwise Alignments

logo    2005, NucleaRDB.


The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       Q7Z2V9_HUMAN
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      HSM806629_2
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 1007.83 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

Q7Z2V9_HUMAN       1 MNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCR 
                     MNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCR 
                     MNTTDNGVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCR 
HSM806629_2        1 aaaagaggatctgatggagagactggtatggtagttacaacaacgttta 
                     taccaagtagtgctggagccgaaagccggaggagttgggtgagatacgg 
                     gtcacctcctgttctgcaaaaactgaccttgcgtccaccttgtctttcg 


Q7Z2V9_HUMAN      50 FSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDG 
                     FSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDG 
                     FSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDG 
HSM806629_2      148 tacctgggagaaactattctaattaggaaagggcagcgaaaaaaaatgg 
                     tggagttaaaagaaggaggtgagtgcgtaaactaaagagtgcgggctag 
                     ctgatttcgcagtatattaaagttagagaaataatatcaaccaacattc 


Q7Z2V9_HUMAN      99 SNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQL 
                     SNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQL 
                     SNIPSINTLAQAEVRSRQISVSSPGSSTDINVKKIASIGDVCESMKQQL 
HSM806629_2      295 aaactaaacgcgggctccatgtacgtaagaagaaagaagggtgtaaccc 
                     gatcctactcacatgcgatctcgcgcgcatataatcgtgatgactaaat 
                     ccccctcagaatatgtcgcacactgactcactgatattttctatgaggc 


Q7Z2V9_HUMAN     148 LVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILL 
                     LVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILL 
                     LVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMMYKDILL 
HSM806629_2      442 tgtggtgatacgttgtctggcggctagcgggctccggaaataatagatc 
                     ttttagcaatcctgatctaaatcttgcacgaatttgccagcttaaattt 
                     acggagtatttcctaaagttggaggatcaggcagtatagacggtattgt 


Q7Z2V9_HUMAN     197 LGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVF 
                     LGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVF 
                     LGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACLKAIVF 
HSM806629_2      589 tgaatgaccaatgggaacggacgcggcgactcgacaggagtgttagagt 
                     tgaaattagaggatatggtcagttaattgctaatataaaaacgtacttt 
                     gacctttcccctatgtctgctttatggtaataacgttctgtttagatat 


Q7Z2V9_HUMAN     246 FDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPT 
                     FDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPT 
                     FDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPT 
HSM806629_2      736 tgcggagcagcgaaaaaatcgcagtggtaagcctgtcgatggtccccca 
                     tacacagtgactataatgtatatgtaaataagaaacgggtgatttttcc 
                     ttataagactaaatgcggcaggctggcccttggtccgggtaggtgcgca 


Q7Z2V9_HUMAN     295 LQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPH 
                     LQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPH 
                     LQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPH 
HSM806629_2      883 ccaaatcaagcactgactgagaagacccgactgggtaggacccccaccc 
                     tagtcgattaatattattgttataattaatttggccaaggataactaca 
                     ggccggagtgaagttattggtatctatgagaatgtcttcttcttagtat 


Q7Z2V9_HUMAN     344 LSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIAAN 
                     LSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIAAN 
                     LSQDPLTGQTILLGPMSTLVHADQISTPETPLPSPPQGSGQEQYKIAAN 
HSM806629_2     1030 ttcgctagcaactgcatacgcggcatacgaccctcccgtgcgctaagga 
                     tcaactcgactttgctccttacaatcccacctccccagcgaaaaatcca 
                     gtacaataatatatcgaagttacgcattacactcaaactgaagcaatac 


Q7Z2V9_HUMAN     393 QASVISHQHLSKQKQL                                  
                     QASVISHQHLSKQKQL                                  
                     QASVISHQHLSKQKQL                                  
HSM806629_2     1177 cgtgatcccctacact                                  
                     accttcaaatcaaaat                                  
                     aaactacgtccaagag                                  


//


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005