NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       Q20379_CAEEL
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      CEF44A2_7
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 949.78 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

Q20379_CAEEL       1 MYFLEGLVAQDKKCTICSRPASTRNHGVLSCSACKMFFARTVQNKLKYE 
                     MYFLEGLVAQDKKCTICSRPASTRNHGVLSCSACKMFFARTVQNKLKYE 
                     MYFLEGLVAQDKKCTICSRPASTRNHGVLSCSACKMFFARTVQNKLKYE 
CEF44A2_7          1 attcggcggcgaataattccgtacacggcttagtaattgaagcaacatg 
                     tattagttcaaaagctgcgccccgaagttcggcgatttcgctaaataaa 
                     gttaacagtatggtaatcaaacttttttagctatagtccattgtaaacg 


Q20379_CAEEL      50 CKKENQCLGNFSHRICQSCRFEKCLKLGMRCSTTNDFIINIEHSSDKKF 
                     CKKENQCLGNFSHRICQSCRFEKCLKLGMRCSTTNDFIINIEHSSDKKF 
                     CKKENQCLGNFSHRICQSCRFEKCLKLGMRCSTTNDFIINIEHSSDKKF 
CEF44A2_7        148 taagacttgattccatcttctgattatgacttaaagtaaaagcttgaat 
                     gaaaaagtgatcagtgacggtaagtatgtggcccaatttataaccaaat 
                     caaatatgactttactgatctaatgaaagatttgttttctagtggtaat 


Q20379_CAEEL      99 SRLLQDLVSRDSRTYSKAINFYTLDDPSLSDIIENKKAMKLIKRTPEVQ 
                     SRLLQDLVSRDSRTYSKAINFYTLDDPSLSDIIENKKAMKLIKRTPEVQ 
                     SRLLQDLVSRDSRTYSKAINFYTLDDPSLSDIIENKKAMKLIKRTPEVQ 
CEF44A2_7        295 actccgtgtagacattagaattatggcatagaagaaagaataaaacggc 
                     ggttaattcgaggcacactatactaacgtgattaaaactattagccata 
                     tagtataacgttagcagtctttcgttttgttttataaaggacagaaata 


Q20379_CAEEL     148 STPEEWSFYCAHSKILFFLGFDFINEMSTSDKKILFENNILRTGSLSGA 
                     STPEEWSFYCAHSKILFFLGFDFINEMSTSDKKILFENNILRTGSLSGA 
                     STPEEWSFYCAHSKILFFLGFDFINEMSTSDKKILFENNILRTGSLSGA 
CEF44A2_7        442 tacggtttttgctaactttgtgtaagataagaaactgaaataagtctgg 
                     cccaagctagcacatttttgtattaatccgaaatttaaattgcgctcgc 
                     gtaaagatttacgaaatcgtttcttagcttcggaacatttgataacctc 


Q20379_CAEEL     197 MHAYKANKEIMMTPSGEDYVSEKIHQLFVKSPNIITQISSLVVSKFIEL 
                     MHAYKANKEIMMTPSGEDYVSEKIHQLFVKSPNIITQISSLVVSKFIEL 
                     MHAYKANKEIMMTPSGEDYVSEKIHQLFVKSPNIITQISSLVVSKFIEL 
CEF44A2_7        589 acgtagaagaaaactgggtgtgaaccctgatcaaaacattcggtatagt 
                     tacaacaaatttcccgaaatcaataatttaccattcatcctttcattat 
                     gtttaatagaggaacagctaaggttgtcggttttttgacataatgcaga 


Q20379_CAEEL     246 KVTNEEYVLLVMLFFCNPAISHKLSDKAKESLAKYQKMYCSALFNYCQI 
                     KVTNEEYVLLVMLFFCNPAISHKLSDKAKESLAKYQKMYCSALFNYCQI 
                     KVTNEEYVLLVMLFFCNPAISHKLSDKAKESLAKYQKMYCSALFNYCQI 
CEF44A2_7        736 agaaggtgccgattttacgatcattgagagtcgatcaatttgttattca 
                     atcaaaattttttttgacctcaatcaacaactcaaaatagccttaagat 
                     gtataatagctggttttaatacgggtatggtaaataggtttagctttaa 


Q20379_CAEEL     295 KYKKAAPARLEDLLSLYSVANQANQCFHSLTIFVHLNNQNCQFKKLIAD 
                     KYKKAAPARLEDLLSLYSVANQANQCFHSLTIFVHLNNQNCQFKKLIAD 
                     KYKKAAPARLEDLLSLYSVANQANQCFHSLTIFVHLNNQNCQFKKLIAD 
CEF44A2_7        883 ataaggcgatggcttttaggacgacttcataatgccaacatctaatagg 
                     aaaaccccgtaattctagtcaacaagtagtctttataaaagataattca 
                     acaaatacaaattaaactcctattacttcgctttttttattatgggatc 


Q20379_CAEEL     344 TWMSTLKNMNDSSLATRGLPFAAPAIHDLTSGRHTRAPNPM         
                     TWMSTLKNMNDSSLATRGLPFAAPAIHDLTSGRHTRAPNPM         
                     TWMSTLKNMNDSSLATRGLPFAAPAIHDLTSGRHTRAPNPM         
CEF44A2_7       1030 ataaacaaaagttcgacgtctggcgacgcatgccaagcaca         
                     cgtgctaataacctccggtctcccctaatccggacgccact         
                     gggtcgacgcttaatcacggctacaactcagattaacgtcg         


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005