NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       O45521_CAEEL
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      CEF44G3_10
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 768.07 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

O45521_CAEEL       1 MSSQNAKSIGGILETSTVPLVIQPQIVNDPAQNNITLPITLCAVCGDTS 
                     MSSQNAKSIGGILETSTVPLVIQPQIVNDPAQNNITLPITLCAVCGDTS 
                     MSSQNAKSIGGILETSTVPLVIQPQIVNDPAQNNITLPITLCAVCGDTS 
CEF44G3_10         1 aaacagataggatgatagccgacccagagcgcaaaaccaactggtggat 
                     tggaacactggttaccctctttacattaaccaaatctctctgctggacc 
                     gccatggactctgataagtgccaggtatccgaccattacgttattgctt 


O45521_CAEEL      50 NGNHYGVPTCFGCSGFFRRTVRNKLVHGCWNGDGNCVIDKANRNRCKSC 
                     NGNHYGVPTCFGCSGFFRRTVRNKLVHGCWNGDGNCVIDKANRNRCKSC 
                     NGNHYGVPTCFGCSGFFRRTVRNKLVHGCWNGDGNCVIDKANRNRCKSC 
CEF44G3_10       148 agactggcattgtagttaaagaaatgcgttagggatgagagacaatatt 
                     agaaagtccgtggggttggctgaattagggagagagttaacagaggacg 
                     cattctgactcactgccaactacggatatgtacactgttagcgcgcgct 


O45521_CAEEL      99 RIKKCFKKGMNKNAVQPERTSHSYTVEYVELPSFREYSKGLLPTHSDRL 
                     RIKKCFKKGMNKNAVQPERTSHSYTVEYVELPSFREYSKGLLPTHSDRL 
                     RIKKCFKKGMNKNAVQPERTSHSYTVEYVELPSFREYSKGLLPTHSDRL 
CEF44G3_10       295 caaattaagaaaaggccgaatcataggtggtcttcgttagcccactgcc 
                     gtaagtaagtaaactacagccagactaatatcctgaacagttccacagt 
                     atagccggggtgttgacgatctcctagtcggcacagtcgatgttctttc 


O45521_CAEEL     148 RFQHEHAQHEIDTSSVLVHLKNALQWVQQFSLFAVLSDVEKSQIILTQW 
                     RFQHEHAQHEIDTSSVLVHLKNALQWVQQFSLFAVLSDVEKSQIILTQW 
                     RFQHEHAQHEIDTSSVLVHLKNALQWVQQFSLFAVLSDVEKSQIILTQW 
CEF44G3_10       442 atccgcgccgagaatgcgccaagcctgccttctggctgggaacaacact 
                     gtaaaacaaatacgctttataactagtaatcttcttcataagatttcag 
                     acacattatatcaccgattgacacgggagtgccagtcttagcgcagcgg 


O45521_CAEEL     197 PHLLCLALFENSEKIFIDEKFAQLAEKFKSLELSAQDYFLLKGIIIFTE 
                     PHLLCLALFENSEKIFIDEKFAQLAEKFKSLELSAQDYFLLKGIIIFTE 
                     PHLLCLALFENSEKIFIDEKFAQLAEKFKSLELSAQDYFLLKGIIIFTE 
CEF44G3_10       589 cccttcgttgatgaataggatgccggatatcgctgcgttctagaaatag 
                     cattgtcttaacaatttaaatcatcaatactatccaaatttagttttca 
                     attgccggcaccaaccctaataagtgacaccatgggttccggatttcga 


O45521_CAEEL     246 TKDGTDLKFDRQLDICIGLLNQLHLESSKSKSGRLLFLLGELKSYSTRQ 
                     TKDGTDLKFDRQLDICIGLLNQLHLESSKSKSGRLLFLLGELKSYSTRQ 
                     TKDGTDLKFDRQLDICIGLLNQLHLESSKSKSGRLLFLLGELKSYSTRQ 
CEF44G3_10       736 aaggagcatgcccgatagccactccgttatatgacctccggcatttaac 
                     caagcatatagatatgtgttaatataccacacggtttttgatacaccga 
                     catcttcactcattctcctctggcggtagcatagtatcccgtactttag 


O45521_CAEEL     295 LESLLDLKACEIVISFL                                 
                     LESLLDLKACEIVISFL                                 
                     LESLLDLKACEIVISFL                                 
CEF44G3_10       883 cgtccgcagtgagaatc                                 
                     tacttatacgatttgtt                                 
                     tatcgttattgtgtttt                                 


//


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005