NucleaRDB: Pairwise Alignments

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The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       O17934_CAEEL
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      CEK06B4_10
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 994.37 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

O17934_CAEEL       1 MFTLARVLNNIGSASSNEPIPYCLICSEVADGNHFGVAAACRACAAFFR 
                     MFTLARVLNNIGSASSNEPIPYCLICSEVADGNHFGVAAACRACAAFFR 
                     MFTLARVLNNIGSASSNEPIPYCLICSEVADGNHFGVAAACRACAAFFR 
CEK06B4_10         1 atacgcgtaaagagttagcactttatagggggactgggggtagtggttc 
                     ttctcgttaatggcccaactcagttggatcagaatgtcccggcgccttg 
                     gccattggcttactactagtattgtttgtttgtttaatagtatctatcc 


O17934_CAEEL      50 RTVQHNKIHECGRNGQCFFLSCKFLLVGFQISPLSSDARSMCKACRYGK 
                     RTVQHNKIHECGRNGQCFFLSCKFLLVGFQISPLSSDARSMCKACRYGK 
                     RTVQHNKIHECGRNGQCFFLSCKFLLVGFQISPLSSDARSMCKACRYGK 
CEK06B4_10       148 cagccaaacgtgaagctttcttatttggtcatccatggcaatagtatga 
                     gctaaaataagggagagtttcgattttgtatcctgcacggtgacggaga 
                     cacactgccgtgatgactcaacgtagcgtaaaaatacagcgtaccgctg 


O17934_CAEEL      99 CLEMGMQRSSVQQRREQLGKRLNISDDRGKPVLNKLRRAYEMLILNRKH 
                     CLEMGMQRSSVQQRREQLGKRLNISDDRGKPVLNKLRRAYEMLILNRKH 
                     CLEMGMQRSSVQQRREQLGKRLNISDDRGKPVLNKLRRAYEMLILNRKH 
CEK06B4_10       295 tcgagaccttgccacgccgaccaatggcgacgcaatcagtgatataaac 
                     gtatgtagcctaaggaatgagtatcaaggacttaatggcaattttagaa 
                     ctagagaaaggagataacgatgtcttttagagttggaagcagatacgac 


O17934_CAEEL     148 VHNRRENQAPRAIGFNELPIVFQNESTSIYQFLWEAFPEYSMLLPDTKL 
                     VHNRRENQAPRAIGFNELPIVFQNESTSIYQFLWEAFPEYSMLLPDTKL 
                     VHNRRENQAPRAIGFNELPIVFQNESTSIYQFLWEAFPEYSMLLPDTKL 
CEK06B4_10       442 gcaacgacgccgagtagccagtcagtaaatctctggtcgttacccgaac 
                     taaggaaaccgctgtaatctttaaaccgtaattgactcaactttcacat 
                     gttgggcaacaccctcgtacgtacggacatgccgaatcgccgttacaac 


O17934_CAEEL     197 AFFKNFFLSFCLFESSFNGCSAKQKNVMLIPSGDYIDLAHSESFFTNDH 
                     AFFKNFFLSFCLFESSFNGCSAKQKNVMLIPSGDYIDLAHSESFFTNDH 
                     AFFKNFFLSFCLFESSFNGCSAKQKNVMLIPSGDYIDLAHSESFFTNDH 
CEK06B4_10       589 gttaattttttctgattagttgacaagacactggtagtgctgtttaagc 
                     cttaatttctgttagctaggccaaaattttccgaatatcacacttcaaa 
                     atcatccggctatgcgttataagaatggctactccctgtttagtccctt 


O17934_CAEEL     246 QTFTERDNIEILAQRLKLIQSSITVPLSAENVDIYEFLALAGIILLESD 
                     QTFTERDNIEILAQRLKLIQSSITVPLSAENVDIYEFLALAGIILLESD 
                     QTFTERDNIEILAQRLKLIQSSITVPLSAENVDIYEFLALAGIILLESD 
CEK06B4_10       736 catagagaagacgcacatacttaagctaggaggatgtcgcggaactgtg 
                     actcagaatattcagtattacctctctgcaatataattctcgttttaca 
                     atctaacttaactagaaaaaatattggttatatctgccgtgtctcgagt 


O17934_CAEEL     295 SESEADFQEEAVKIKSNIIKDLLFHYQCINIYDDAAMRLGAVLSILPSI 
                     SESEADFQEEAVKIKSNIIKDLLFHYQCINIYDDAAMRLGAVLSILPSI 
                     SESEADFQEEAVKIKSNIIKDLLFHYQCINIYDDAAMRLGAVLSILPSI 
CEK06B4_10       883 tgtgggtcggggaaaaaaaagcctctctaaatggggaacgggttaccta 
                     cacacataaactatagattaatttaaagtataaacctgtgcttcttcct 
                     tgaacttaaatggtgctccgtattctatattttcaaggtcatgcataat 


O17934_CAEEL     344 QVCCSRSNNFLIINSKDVSESQSPFSRIHGNQKYAQFVRSSQESLRHVL 
                     QVCCSRSNNFLIINSKDVSESQSPFSRIHGNQKYAQFVRSSQESLRHVL 
                     QVCCSRSNNFLIINSKDVSESQSPFSRIHGNQKYAQFVRSSQESLRHVL 
CEK06B4_10      1030 cgtttcaaattaaataggtgactcttcacgacatgctgcttcgttccgc 
                     atggcggaattttacaatcagacctcgtagaaaacattgccaactgatt 
                     attcggccttgtactattagcgagtaaatataattatactcaataattc 


O17934_CAEEL     393 ANFIKFICKFVSI                                     
                     ANFIKFICKFVSI                                     
                     ANFIKFICKFVSI                                     
CEK06B4_10      1177 gataatatatgta                                     
                     cattattgattct                                     
                     cccaatttatttt                                     


//


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F.Horn (nucleardbcmbi.kun.nl), 18-Feb-2005