Swiss-Prot entry

ID   Q7ZZY9_PETMA PRELIMINARY;      PRT;   406 AA.
AC   Q7ZZY9;
DT   01-JUN-2003 (TrEMBLrel. 24, Created)
DT   01-JUN-2003 (TrEMBLrel. 24, Last sequence update)
DT   01-MAR-2004 (TrEMBLrel. 26, Last annotation update)
DE   Vitamin D receptor.
GN   Name=VDR;
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Hyperoartia; 
OC   Petromyzontiformes; Petromyzontidae; Petromyzon. 
OX   NCBI_TaxID=7757;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Spleen;
RX   MEDLINE=22630542; PubMed=12746335 [NCBI, ExPASy, EBI, Israel, Japan]; DOI=10.1210/en.2002-221101;
RA   Whitfield G.K., Dang H.T.L., Schluter S.F., Bernstein R.M., Bunag T.,
RA   Manzon L.A., Hsieh G., Encinas Dominguez C., Youson J.H.,
RA   Haussler M.R., Marchalonis J.J.;
RT   "Cloning of a functional vitamin D receptor from the lamprey
RT   (Petromyzon marinus), an ancient vertebrate lacking a calcified
RT   skeleton and teeth.";
RL   Endocrinology 144:2704-2716(2003).
CC   -!- SUBCELLULAR LOCATION: Nuclear (By similarity).
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
DR   EMBL; AY249863; AAP05810.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   HSSP; P11473; 1KB2. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
DR   GO; GO:0005634; C:nucleus; IEA.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA.
DR   GO; GO:0003700; F:transcription factor activity; IEA.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA.
DR   GO; GO:0006350; P:transcription; IEA.
DR   InterPro; IPR000536; Hrmon_recept_lig.
DR   InterPro; IPR001723; Stdhrmn_receptor.
DR   InterPro; IPR000324; VitD_receptor.
DR   InterPro; IPR001628; Znf_C4steroid.
DR   InterPro; Graphical view of domain structure.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   Pfam; Graphical view of domain structure.
DR   PRINTS; PR00398; STRDHORMONER.
DR   PRINTS; PR00047; STROIDFINGER.
DR   PRINTS; PR00350; VITAMINDR.
DR   ProDom; PD000035; Znf_C4steroid; 1.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain ]
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   PROSITE; PS00031; NUCLEAR_RECEPTOR; 1.
DR   HOVERGEN [Family / Alignment / Tree]
DR   ProtoMap; Q7ZZY9.
DR   PRESAGE; Q7ZZY9.
DR   ModBase; Q7ZZY9.
DR   SMR; Q7ZZY9.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   DNA-binding; Metal-binding; Nuclear protein; Receptor; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
SQ   SEQUENCE   406 AA;  45974 MW;  4392E365302ECB72 CRC64;
     MMATQNMTVS TSNALEDDEE GGVPKVCGVC GDKATGYHFN AMTCEGCKGF FRRSMKRSAS
     FTCPFEGKCN ITKDNRRHCQ ACRLKRCRDI GMMKELIMTE EEVQRKKEII MKRKLEDSAR
     EVHTPQLLEE QERLIATLIE AHRKTYDASY SDFSQFRPPK RGDGSPECRN ATNPFLMSLL
     NSDMDELPKA SASGAEAAAG DELSMLPHLA DLVSYSIQKV IGFAKMIPGF KELCTEDQIS
     LLKASAIEII ILRSNESFTM EDNSWTCGSN EFKYQIGDVM QAGHKLELLE PLVKFQVNMK
     KLDLHEAEHV LLMAICLFSP DRPGVQDRCR VEEVQEHLTE TLRAYIACRH PLSCKHMLYT
     KMVEKLTELR SLNEEHSKQY LQISQDAVNK EDLPPLLLEV FGNPTA
//