Swiss-Prot entry

ID   Q13771_HUMAN PRELIMINARY;      PRT;   730 AA.
AC   Q13771;
DT   01-NOV-1996 (TrEMBLrel. 01, Created)
DT   01-NOV-1996 (TrEMBLrel. 01, Last sequence update)
DT   01-MAR-2004 (TrEMBLrel. 26, Last annotation update)
DE   Androgen receptor.
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; 
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. 
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Testis;
RX   MEDLINE=90258935; PubMed=2342476 [NCBI, ExPASy, EBI, Israel, Japan];
RA   Govindan M.V.;
RT   "Specific region in hormone binding domain is essential for hormone
RT   binding and trans-activation by human androgen receptor.";
RL   Mol. Endocrinol. 4:417-427(1990).
CC   -!- SUBCELLULAR LOCATION: Nuclear (By similarity).
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
DR   EMBL; M73069; AAA51735.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   HSSP; P10275; 1E3G. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
DR   GO; GO:0005634; C:nucleus; IEA.
DR   GO; GO:0004882; F:androgen receptor activity; IEA.
DR   GO; GO:0004872; F:receptor activity; IEA.
DR   GO; GO:0005496; F:steroid binding; IEA.
DR   GO; GO:0003700; F:transcription factor activity; IEA.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA.
DR   GO; GO:0006350; P:transcription; IEA.
DR   InterPro; IPR001103; Andrgn_receptor.
DR   InterPro; IPR000536; Hrmon_recept_lig.
DR   InterPro; IPR001628; Znf_C4steroid.
DR   InterPro; Graphical view of domain structure.
DR   Pfam; PF02166; Androgen_recep; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   Pfam; Graphical view of domain structure.
DR   PRINTS; PR00521; ANDROGENR.
DR   PRINTS; PR00047; STROIDFINGER.
DR   ProDom; PD000035; Znf_C4steroid; 1.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain ]
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   PROSITE; PS00031; NUCLEAR_RECEPTOR; 1.
DR   HOVERGEN [Family / Alignment / Tree]
DR   ProtoMap; Q13771.
DR   PRESAGE; Q13771.
DR   ModBase; Q13771.
DR   SMR; Q13771.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   DNA-binding; Metal-binding; Nuclear protein; Receptor;
KW   Steroid-binding; Transcription; Transcription regulation; Zinc;
KW   Zinc-finger.
SQ   SEQUENCE   730 AA;  79149 MW;  918B47C3B41B80C9 CRC64;
     MQLLQQQQQE AVSEGSSSGR AREASGAPTS SKDNYLGGTS TISDNAKELC KAVSVSMGLG
     VEALEHLSPG EQLRGDCMYA PLLGVPPAVR PTPCAPLAEC KGSLLDDSAG KSTEDTAEYS
     PFKGGYTKGL EGESLGCSGS AAAGSSGTLE LPSTLSLYKS GALDEAAAYQ SRDYYNFPLA
     LAGPPPPPPP PHPHARIKLE NLLDYGSAWA AAAAQCRYGD LASLHGAGAA GPGSGSPSAA
     ASSSWHTLFT AEEGQLYGPC GGGGGGGGGG GGGGGGEAGA VAPYGYTRPP QGLAGQESDF
     TAPDVWYPGG MVSRVPYPSP TCVKSEMGPW MDSYSGPYGD MRLETARDHV LPIDYYFPPQ
     KTCLICGDEA SGCHYGALTC GSCKVFFKRA AEGKQKYLCA SRNDCTIDKF RRKNCPSCRL
     RKCYEAGMTL GARKLKKLGN LKLQEEGEAS STTSPTEETT QKLTVSHIEG YECQPIFLNV
     LEAIEPGVVC AGHDNNQPDS FAALLSSLNE LGERQLVHVV KWAKALPGLR NLHVDDQMAV
     IQYSWMGLMV FAMGWRSFTN VNSRMLYFAP DLVFNEYRMH KSRMYSQCVR MRHLSQEFGW
     LQITPQEFLC MKAMLIFFFF LLLFSIIPVD GLKNQKFFDE LRMNYIKELD RIIACKRKNP
     TSCSRRFYQL TKLLDSVQPI ARELHQFTFD LLIKSHMVSV DFPEMMAEII SVQVPKILSG
     KVKPIYFHTQ
//