Swiss-Prot entry

ID   O45560_CAEEL PRELIMINARY;      PRT;   253 AA.
AC   O45560;
DT   01-JUN-1998 (TrEMBLrel. 06, Created)
DT   01-JUN-1998 (TrEMBLrel. 06, Last sequence update)
DT   01-MAR-2004 (TrEMBLrel. 26, Last annotation update)
DE   Hypothetical protein F54B8.2.
GN   ORFNames=F54B8.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; 
OC   Rhabditidae; Peloderinae; Caenorhabditis. 
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bristol N2;
RX   MEDLINE=99069613; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan];
RA   none;
RT   "Genome sequence of the nematode C.elegans: A platform for
RT   investigating biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bristol N2;
RA   Barlow K.;
RL   Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Receptor for both mineralocorticoids (MC) such as
CC       aldosterone and glucocorticoids (GC) such as corticosterone or
CC       cortisol. Binds to mineralocorticoid response elements (MRE) and
CC       transactivates target genes. The effect of MC is to increase ion
CC       and water transport and thus raise extracellular fluid volume and
CC       blood pressure and lower potassium levels (By similarity).
CC   -!- SUBCELLULAR LOCATION: Nuclear (By similarity).
DR   EMBL; Z93383; CAB07624.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   PIR; T22619; T22619.
DR   Ensembl; F54B8.2; Caenorhabditis elegans. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   WormBase; WBGene00010017; F54B8.2.
DR   WormPep; F54B8.2; CE16104. [WormPep / WormBase / WorfDB]
DR   GO; GO:0005634; C:nucleus; IEA.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA.
DR   GO; GO:0003700; F:transcription factor activity; IEA.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA.
DR   InterPro; IPR000536; Hrmon_recept_lig.
DR   InterPro; Graphical view of domain structure.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; Graphical view of domain structure.
DR   SMART; SM00430; HOLI; 1.
DR   CMR; O45560.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain]
DR   ProtoMap; O45560.
DR   PRESAGE; O45560.
DR   ModBase; O45560.
DR   SMR; O45560.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   Hypothetical protein; Nuclear protein; Transcription regulation.
SQ   SEQUENCE   253 AA;  29639 MW;  79006B54F4E267FF CRC64;
     MNIKSLLQNT SLEPLTDFIS EVNFNRCTLY LNSIPKYRDY TIGQIVQNDV IEYIPRCHPM
     NYRDWFYLVA VSTSDFLRKF PFVYQSSSRD QSFILQKNFV KVASFCEAFR YYLLGEKQLT
     FPDGSNILIE DLGIELGERI KFRLVAKCCE LQITNEEFLL LLVLIFSSPA IEDLSDTGNL
     LLSSFQSYYS SSLLKYCMLT FYQDGPIRFT KLLDVFQVVG QHYEDLNRYF VFLQLTNPEF
     QLDDIVKKGF NLL
//