Swiss-Prot entry
ID NR2F1_BRARE STANDARD; PRT; 411 AA.
AC Q06725;
DT 15-JUL-1999 (Rel. 38, Created)
DT 15-JUL-1999 (Rel. 38, Last sequence update)
DT 01-MAY-2005 (Rel. 47, Last annotation update)
DE Nuclear receptor Nr2f1 (Steroid receptor homolog SVP 44).
GN Name=nr2f1; Synonyms=svp44;
OS Brachydanio rerio (Zebrafish) (Danio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Cyprinidae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RX MEDLINE=93223680; PubMed=8467797 [NCBI, ExPASy, EBI, Israel, Japan];
RA Fjose A., Nornes S., Weber U., Mlodzik M.;
RT "Functional conservation of vertebrate seven-up related genes in
RT neurogenesis and eye development.";
RL EMBO J. 12:1403-1414(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative receptor that is required in photoreceptor
CC cells precursors during eye development.
CC -!- SUBCELLULAR LOCATION: Nuclear (Potential).
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. NR2
CC subfamily.
CC -!- SIMILARITY: Contains 1 nuclear receptor DNA-binding domain.
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CC This Swiss-Prot entry is copyright. It is produced through a collaboration
CC between the Swiss Institute of Bioinformatics and the EMBL outstation -
CC the European Bioinformatics Institute. There are no restrictions on its
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DR EMBL; X70299; CAA49780.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR EMBL; BC066671; AAH66671.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR PIR; S35333; S35333.
DR HSSP; P19793; 1BY4. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
DR Ensembl; ENSDARG00000017168; Danio_rerio
DR ZFIN; ZDB-GENE-980526-115; nr2f1.
DR InterPro; IPR000536; Hrmon_recept_lig.
DR InterPro; IPR001723; Stdhrmn_receptor.
DR InterPro; IPR008946; Str_ncl_receptor.
DR InterPro; IPR001628; Znf_C4steroid.
DR InterPro; Graphical view of domain structure.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR Pfam; Graphical view of domain structure.
DR PRINTS; PR01282; COUPTNFACTOR.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR ProDom; PD000035; Znf_C4steroid; 1.
DR ProDom [Domain structure / List of seq. sharing at least 1 domain ]
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
DR CMR; Q06725.
DR HOVERGEN [Family / Alignment / Tree]
DR BLOCKS; Q06725.
DR ProtoNet; Q06725.
DR ProtoMap; Q06725.
DR PRESAGE; Q06725.
DR DIP; Q06725.
DR ModBase; Q06725.
DR SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW DNA-binding; Nuclear protein; Receptor; Sensory transduction;
KW Transcription; Transcription regulation; Vision; Zinc-finger.
FT DNA_BIND 73 148 Nuclear receptor-type.
FT ZN_FING 76 96 C4-type.
FT ZN_FING 112 136 C4-type.
SQ SEQUENCE 411 AA; 45482 MW; B0405FB4AEFA0202 CRC64;
MAMVVSVWRD PQEDVAGGPP SGPNPAAQPA REQQQAASAA PHTPQTPSQP GPPSTPGTAG
DKGSQNSGQS QQHIECVVCG DKSSGKHYGQ FTCEGCKSFF KRSVRRNLTY TCRANRNCPI
DQHHRNQCQY CRLKKCLKVG MRREAVQRGR MPPTQPNPGQ YALTNGDPLN GHCYLSGYIS
LLLRAEPYPT SRYGSQCMQP NNIMGIENIC ELAARLLFSA VEWARNIPFF PDLQITDQVS
LLRLTWSELF VLNAAQCSMP LHVAPLLAAA GLHASPMSAD RVVAFMDHIR IFQEQVEKLK
ALHVDSAEYS CIKAIVLFTS DACGLSDAAH IESLQEKSQC ALEEYVRSQY PNQPSRFGKL
LLRLPSLRTV SSSVIEQLFF VRLVGKTPIE TLIRDMLLSG SSFNWPYMSI Q
//