Swiss-Prot entry
ID NR1I3_CALUR STANDARD; PRT; 348 AA.
AC P62044;
DT 05-JUL-2004 (Rel. 44, Created)
DT 05-JUL-2004 (Rel. 44, Last sequence update)
DT 01-MAY-2005 (Rel. 47, Last annotation update)
DE Orphan nuclear receptor NR1I3 (Constitutive androstane receptor)
DE (CAR).
GN Name=NR1I3; Synonyms=CAR;
OS Callorhinus ursinus (Northern fur seal).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Laurasiatheria; Carnivora; Pinnipedia; Otariidae;
OC Callorhinus.
OX NCBI_TaxID=34884;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RA Sakai H., Iwata H., Kim E., Tanabe S., Baba N.;
RT "Identification of constitutive androstane receptor cDNA in northern
RT fur seal (Callorhinus ursinus).";
RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterodimer of NR1I3 and RXR (By similarity).
CC -!- SUBCELLULAR LOCATION: Nuclear (By similarity).
CC -!- DOMAIN: Composed by a short N-terminal domain followed by the DNA
CC binding, hinge, and ligand binding/dimerization domains.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family. NR1
CC subfamily.
CC -!- SIMILARITY: Contains 1 nuclear receptor DNA-binding domain.
CC --------------------------------------------------------------------------
CC This Swiss-Prot entry is copyright. It is produced through a collaboration
CC between the Swiss Institute of Bioinformatics and the EMBL outstation -
CC the European Bioinformatics Institute. There are no restrictions on its
CC use as long as its content is in no way modified and this statement is not
CC removed.
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DR EMBL; AB109554; BAD00039.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR SMR; P62044; 103-348.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR PRINTS; PR00350; VITAMINDR.
DR ProDom; PD000035; Znf_C4steroid; 1.
DR ProDom [Domain structure / List of seq. sharing at least 1 domain ]
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
DR HOVERGEN [Family / Alignment / Tree]
DR BLOCKS; P62044.
DR ProtoNet; P62044.
DR ProtoMap; P62044.
DR PRESAGE; P62044.
DR DIP; P62044.
DR ModBase; P62044.
DR SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW Activator; DNA-binding; Nuclear protein; Receptor; Transcription;
KW Transcription regulation; Zinc-finger.
FT DNA_BIND 8 83 Nuclear receptor-type.
FT ZN_FING 11 31 C4-type.
FT ZN_FING 47 71 C4-type.
SQ SEQUENCE 348 AA; 39432 MW; 05BD1BBDD80DD3DD CRC64;
MASGEDGPRS CMVCGDRATG YHFHALTCEG CKGFFRRTVS KNTGLTCPFA GNCKVNKAQR
RHCPACRLQK CLDAGMKKEM ILSAEALVQR RAKQAQRRAQ WAPVQLSKGQ QELVQTLLGA
HARHVGTMFD QFVQFRPPAH LFIHHQRLPI PVPALPLLKH FAEVNTFMVQ EVIKFTKDLP
LFRSLPMEDQ ISLLKGAAVE ICHIALNTTF CLQTRNFLCG PLCYALEDGV HVGFQEEFLE
LLFRFHATLR RLQLQEPEYV LMAAMALFSP DRPGVTRREE IDRLQEVTAL TLQSYIKGQP
PRPRDRFLYA KLLGLLAELR SIDNAYGYQI QHIQGLSAMM PLLQEICS
//