Swiss-Prot entry

ID   HR3_GALME      STANDARD;      PRT;   557 AA.
AC   P49868;
DT   01-OCT-1996 (Rel. 34, Created)
DT   01-OCT-1996 (Rel. 34, Last sequence update)
DT   01-MAY-2005 (Rel. 47, Last annotation update)
DE   Probable nuclear hormone receptor HR3 (GHR3).
GN   Name=HR3; Synonyms=NR1F4;
OS   Galleria mellonella (Wax moth).
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; 
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea; 
OC   Pyralidae; Galleriinae; Galleria. 
OX   NCBI_TaxID=7137;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=95072627; PubMed=7981726 [NCBI, ExPASy, EBI, Israel, Japan]; DOI=10.1016/0965-1748(94)90105-8;
RA   Jindra M., Sehnal F., Riddiford L.M.;
RT   "Isolation and developmental expression of the ecdysteroid-induced
RT   GHR3 gene of the wax moth Galleria mellonella.";
RL   Insect Biochem. Mol. Biol. 24:763-773(1994).
CC   -!- FUNCTION: Putative receptor whose ligand is not yet known.
CC   -!- SUBCELLULAR LOCATION: Nuclear (Potential).
CC   -!- INDUCTION: By ecdysteroid.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family. NR1
CC       subfamily.
CC   -!- SIMILARITY: Contains 1 nuclear receptor DNA-binding domain.
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CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
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DR   EMBL; U02621; AAA83401.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   HSSP; P03372; 1HCQ. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
DR   InterPro; IPR000536; Hrmon_recept_lig.
DR   InterPro; IPR001723; Stdhrmn_receptor.
DR   InterPro; IPR008946; Str_ncl_receptor.
DR   InterPro; IPR000324; VitD_receptor.
DR   InterPro; IPR001628; Znf_C4steroid.
DR   InterPro; Graphical view of domain structure.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   Pfam; Graphical view of domain structure.
DR   PRINTS; PR00398; STRDHORMONER.
DR   PRINTS; PR00047; STROIDFINGER.
DR   PRINTS; PR00350; VITAMINDR.
DR   ProDom; PD000035; Znf_C4steroid; 1.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain ]
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
DR   BLOCKS; P49868.
DR   ProtoNet; P49868.
DR   ProtoMap; P49868.
DR   PRESAGE; P49868.
DR   DIP; P49868.
DR   ModBase; P49868.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   DNA-binding; Nuclear protein; Receptor; Transcription;
KW   Transcription regulation; Zinc-finger.
FT   DNA_BIND    105    180       Nuclear receptor-type.
FT   ZN_FING     108    128       C4-type.
FT   ZN_FING     144    168       C4-type.
FT   DOMAIN      322    557       Ligand-binding (Potential).
SQ   SEQUENCE   557 AA;  62316 MW;  DA518DB12B978589 CRC64;
     MNNSQFHELF GSQWPPDQHG GHSSASTMLH QAQSPLPQGM RLKREPHTDV QGVMHNQMGM
     DITSGSVADS TSPPPGSSEG MFGSSISGMF MDKKAANSIR AQIEIIPCKV CGDKSSGVHY
     GVITCEGCKG FFRRSQSTVV NYQCPRNKAC VVDRVNRNRC QYCRLQKCLK LGMSRDAVKF
     GRMSKKQREK VEDEVRYHRA QMRAQTDAAP DSVYDAQQQT PSSSDQFHGH YNGYPGYRSP
     LSSYGYGGNA GPALTSNMNI QPQAPQQQPY DVSADYVDST TAYEPKQTGG FLDADFIGHA
     EGDISKVLVK SLAEAHANTN PKLEYVHEMF RKPPDVSKLL FYNSMTYEEM WLDCADKLTG
     MIQNIIEFAK LIPGFMKLSQ DDQILLLKSG SFELAIVRLS RLIDVNREQV LYGDVVLPIR
     ECVHARDPRD VTLVVGIFDA AKTIERLKLT ETELALYQSL VLLWPERHGV RGNPEIQCLF
     NMSMAAMRHE IESNHAPLKG DVTVLDTLLA KIPTFRELSL MHLEALCRFK AAHPHHVFPA
     LYKELFSLDS VLDYTHG
//