NucleaRDB 2 HNF4-like (HNF4,RXR,TLL,COUP,USP)
2005, NucleaRDB.
CONSENSUS GSPADRGGGSQGSLSAGRTSAVPSPGSELPPLIGAGLMGEIGIPQMKHDPIQPASSLIGNAGGSGFPSNNSDSSPPPFAP
RXRA_RAT FLPLDFSTQVNSSSLSSPTGRgmAAPS.LHPSLGPGLGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVP
RXRA_MOUSE FLPLDFSTQVNSSSLNSPTGRgmAVPS.LHPSLGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVP
RXRA_HUMAN TKHFLP..LDFSTQVNSSLTSPTGRGSMAAplHPS.LGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVP
RXRB_HUMAN sePGEAGRD..GMGDSGRDSRSPDSSSPNPLPQGVPPPspLPPSTApaPPPPPMPPPPLG..SPFPVISSSMGSPGLPPP
Q5TJF7_CANFA sePGEAGRD..GMGDSGRDSRSPDSSSPNPLSQGAPpgLPLPPSSApaPPPPPMPPPQLG..SPFPVISSSMGSPGLPPP
RXRB_MOUSE LEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLG..SPFPVISSSMGSPGLPPP
Q6LC96_MOUSE .M.AVP......SL..H.PS............LGPGIGSPLGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVP
Q6MGB3_RAT .M.GD..........SGRDSRSPDSSSPNPLSQGIPPSSPPGPPHTPSAPPPPMPPPPLG..SPFPVISSSMGSPGLpaP
RXRG_MOUSE YSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPyvITSAMGP.PSGAL
RXRG_HUMAN YSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPyvITSAMGP.PSGap
Q5REL6_PONPY YSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPyvITSAMGP.PSGap
RXRA_XENLA TSWTAGY..DFSSQVNS..SSLSSspSLGN..SG..LNNSLGSPTQLPS...PLSSPINGMGPPFSVIspLGPSMAIPST
7UP1_DROME GSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGS
RXRG_CHICK .mhFIKFPAGFGNSPVHASSTSVSPSSSL..SVgdGHHNYLEasRALPSPMNTIGSP.VNALGsyRVIASSIGSHplSSS
RXRB_BRARE gsRDSR.......SPDS..SSV...SS.....PPSGQRSppSAAAMtpPITSAVNSPISSMGSPFSVISSSLGSPCLPGT
Q6INZ0_XENLA gsP.DTSSL.SPPL.GH..SFS.D........TPPPPSAPLHPSMVGSAMTSSVNSPLGSIGSPFPVINCSVGSPGIPGT
Q91613_XENLA gsP.DTSSL.SPPL.GH..SFS.D........TPPPPSAPLHPSMVGSAMTSSVNSPLGSIGSPFPVINCSVGSPGIPGT
RXRG_XENLA YSST.YF...NSSLHAH.STSVSSssLDTH..PGYMGNSLNGPRSMTTN.MNSMCSP.GNNIGLPyvIASSMGPHSLPSP
RXRA_BRARE .mnNDT....YLHL.SS..SLQVAHGHL...SSP..PSQPPLSSMVSHHHPSI....I.NGLGSPyvIT..SSSLGSPSA
Q86GV5_BRAFL .M.AMA.........VS.TWR.....E.....PGED....LSSP.DKQQQQQPVPAP..V.PGPGPQQ....PPPSQPPG
COT1_MOUSE AMV...........VSS..WR..D.........P..........QD..D..........VAGGNP.G.....GPNPA.AQ
COT1_HUMAN AMV...........VSS..WR..D.........P..........QD..D..........VAGGNP.G.....GPNPA.AQ
COT1_BOVIN AMV...........VSS..WR..D.........P..........QD..D..........VAGGNP.G.....GPNPA.AQ
Q62681_RAT AMV...........VSS..WR..D.........P..........QD..D..........VAGGNP.G.....GPNPA.AQ
Q9BMU6_AEDAE ysPSTATGFYNPRGQGSEIGALELgpPHGAWRDPTGLGSHL.PVSSTSEDITTLGGGnsSMQSNTSIDKKDFIS.SASAG
Q6DHP9_BRARE .MDTHD...TYLHLHSSpnSS....PS....QPPvgHPSVISSSRPLPSPMSTLGSSMNGLPSPYSVITPSLSSPSISLP
COT2_BOVIN AMV............VS.TWR..D.........P..Q.....DE.VPG...........S.QGSQASQA....PPVPGP.
COT2_HUMAN AMV............VS.TWR..D.........P..Q.....DE.VPG...........S.QGSQASQA....PPVPGP.
COT2_MOUSE AMV............VS.TWR..D.........P..Q.....DE.VPG...........S.QGSQASQA....PPVPGP.
COT2_RAT AMV............VS.TWR..D.........P..Q.....DE.VPG...........S.QGSQASQA....PPVPGP.
NR2F1_BRARE AMV............VS.VWR..D.........P...........Q.ED..........VAGGPPSG......PNPA.AQ
Q91430_BRARE AMVVWR.........GS..Q...D.......DVAETHGT.LSS..QT.Q..........GGLSLPTPQ.........PGQ
Q6PHF2_BRARE AMV............VS.VWR..D.........P...........Q.ED..........VAGGPPSG......PNPA.AQ
Q9W745_XENLA AMV...........VSS..WR..D.........P...........Q.ED..........VAGGNP.G.....GPNP.GV.
Q91840_XENLA .M.............VG..S.............A...........MTSS....VNSPLGSIGSPFPVINCSVGSPGIPGT
Q8T5C6_BIOGL .M..DRSEG.MDTLENS.MPSGMSMGM....TMG.GHQGHP.PP.dkPD.ISSLTSP.TSTHgyGFGPG.GMPSMASSTQ
COT2_CHICK AMV............VG.AWR..D.........P..Q.....D.DVP............GAQGTQP..A.....PAPPVQ
Q8MX78_BRAFL GSPGGA.....P...AS..STTPNPTTQH...QPMHYSAPPHIPSMTSSGPHITSPplSSGQptPSVLT...SSHPLhvK
Q6DCH6_XENLA AMV...........VSG..WR..D.........P...........Q.ED..........VAGGNP.G.....GPNP.GV.
Q8VCR0_MOUSE .MPPPP.......L.GS........PF......PV.....I.SSSMGSP..........G.LPPPAP.......PG.FSG
Q7ZXI7_XENLA AMV............VG.AWR..D.........P..Q.....D.DMPG...........S.QTTQAP.........PGP.
Q9PS79_9PIPI AMV............VG.AWR..D.........P..Q.....D.DMPG...........S.QTTQAP.........PGPT
Q8UUM6_ORYLA .M.T............S...............LP.....PISTSGVNS....PV....SSIGSPFSVISSSLGSPCLPGT
RXRD_BRARE .M.............NS...............LP......PSTSAVSS....PVSSVD.S..PLSAVSS.SIGSPGVPGT
Q66TQ0_9CAEN .M.............GHQVEACQVAMHMG..VPGMGGMGGPHQPDIKPD.ISTLNPP.SStpGFSYPGYGGMPGMPSSTQ
Q6GN21_XENLA as.RSQTEVSQTALMDGTTQRIQLVPSESNVSVP..QRIQIVTDPQTGQKIQIVTALDQSGVSKQFILTNNDGSLPSKVI
7UP2_DROME GSVATGGGGTTPSSVASQQSAVIKQDLSCPSLNQAGSGHHPGIKEDLSSSLPSANGGSAGGHHSGSGSGSGSGVNPGHGS
Q6V7U7_LOCMI .M...E.........GS..ERGIS..LENN.LSIS.SMGPQSPLDMKPD...TA.SLISS..GSFSP.......TG.GP.
Q66J63_XENLA asRSHT.EVSQTALMDGTTQRIQLVPSESSVSVP..QRIQIVTDPQTGQKIQIVTALDQSGTNKQFIFTNNDGSLPSKVI
O76241_UCAPU esVSSI.......IHGS.QQRAWTPGL....DIGM.SGS.L.D.RQSP...LSV.APDTVSLLSPAPSF....STANGGP
Q8IPF2_DROME EAEAGR.RRRRRDSSASR.TASSDESES.HIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNG
Q91720_XENLA AMV...........VNP..W.....QE.....DI........P.GVPGS........QMN...NPPG.........LCNQ
Q5RCZ5_PONPY .M.ATIEEI......AH..Q............IIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVI
Q95K90_MACFA .M.ATIEEI......AH..Q............IIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVI
RXRG_BRARE .M...............................P...........VPEQ..............KQ...............
Q15625_HUMAN .M.ATIEEI......AH..Q............IIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVI
Q9VLI7_DROME LSVTDDQQLMKVNKVEKMEQELHDPESESHIMHADALASAYPAASQPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNG
NR2F5_BRARE AMV...........VNQ..W.....QE.....NI........SA.DPG...........S.Q.LQ...........MCSQ
Q9GSG8_AEDAE LSVAAI.......IQag.dRTLPLAGLAGFDavG..HMGPVSPQDMKPDLKPDISLLNGSVGPFSPGNNCGPASPGAFNQ
USP_MANSE SSVAKK..DKRT...MS.VTALINR...AWPLTPAPH..QQ..QSMPSS..QP.....SN..FLQP.LA..TPSTTPSVE
USP_CHOFU SSVAKK...DKP..TMS.VTALINW......ARPAPPG..P.PQPQSAS...PAPAAMLQQLPTQSMQSLNHIPTVDCSL
Q6PH18_BRARE AMV............VS.AWR........................D.................PQ...............
TR4_HUMAN TSPSPR...IQIISTDS...AV...........ASPQRIQIVTDQQTGQKIQIVTAVDAS.GSpqFILT...SPDGAGTG
TR4_MOUSE TSPSPR...IQIISTDS...AV...........ASPQRIQIVTDQQTGQKIQIVTAVDAS.GSsqFILT...SPDGAGTG
Q6P0E6_BRARE AMV............VS.AWR........................D.................PQ...............
TR4_RAT TSPSPR...IQIISTDS...AVRS.........P..QRIQIVTDQQTGQKLQIVTAVDAS.GSsqFILT...SPDGAGTG
Q9U3Y3_AEDAL LSVAAI.......IQag.dRTLPLAGLAGFDavG..HMGPLSPQDMKPDLKPDISLLNGS.VGPFS.LRHNCgsPGAFNQ
Q9GSG7_AEDAE .mpSDR..........G.FDAA.L........VG..HMGPLSPQDMKPDLKPDISLLNGSVGPFSPGNNCGPASPGAFNQ
Q9U7D9_LOCMI .M...E.........GS..ERGIS..LENN.LSIS.SMGPQSPLDMKPD...TA.SLISS..GSFSP.......TG.GP.
USP_BOMMO SSVAKK..DKRT...MS.VTALINR........A.WPMT.PSPQQQ..Q..QMV....PSTQHSNFLHAMATPSTTPNVE
Q8VIJ3_MOUSE .M.ATIEEI......AH..Q............IIDQQMGEIVTEQQTGQKIQIVTALDHSTQGKQFILA.....NHEGST
Q8VIJ4_RAT .M.ATIEEI......AH..Q............IIDQQMGEIVTEQQTGQKIQIVTALDHSTQGKQFILA.....NHEGST
EAR2_HUMAN AMVT...........GG..W.............G.......GPGGDT............N....G.V....D.....KA.
HNF4_DROME .MHADA.......L.AS...AY..........PAA.......S..QPHSPIGLALSPNGGGLGLSNSSNQSSENFALCNG
Q9NG48_APIME esVTAI...IQGTQAQH..WSR...........GNTWLS.LDNSNMssS..........V..GPQSPLD..MKPDTAsnP
Q62152_MOUSE .M.ATIEEI......AH..Q............IIDQQMGEIVTEQQTGQKMQIVTALDHSTQGKQFILA.....NHEGST
Q6GL59_XENTR AMVS...........GG..W.............G...........DP............N....GD..TN.......GV.
Q7T0T7_XENLA AMVS...........GG..W.............G...........DP............N....GD..TN.......GV.
Q922G8_MOUSE AMVT...........GG..W.............G...........DPG...........G.DTNG.V....D.....KA.
Q9NFY1_TENMO TM.............ES..T...DR........A......L.SL.D..Q........NLSMGSLGAP....HSPLDMKPD
EAR2_MOUSE AMVT...........GG..W.............G...........DPG...........G.DTNG.V....D.....KA.
Q6P117_BRARE AMV..R.........GG..W.............G...........DP..........Ngn..GLGD...........K..
EAR2_RAT AMVT...........GG..W.............G.......GPGGDT............N....G.V....D.....KA.
USP_DROME .mnCDQ........DAS..FRL.S........HI....KE....EVKPD.ISQLN..DSN.NSSFSPKA...ESPVPFMQ
O45117_CHITE .mvAAIIEQAQNRWMDH.nSRsqFQGSYCIDslG..HMGPLSPP.DlpD.ISLlnNTNNN.NSNSSHNNLNHHNtpLPVL
Q8CFY1_MOUSE .M...R.......L..S..KT...........LA..........GM...................D..........M.A.
Q5QPB8_HUMAN .M...R.......L..S..KT...................LVD..M...................D..........M.A.
Q962I5_LUCCU .M..D..........NG.EQ...DAGF....RLA..PMS...PQEIKPD.ISLLNE..NNT..SSYS.....PKPGSPNP
Q6P115_BRARE AMVS...........GG..W.............A.........................N..PNGS..A.....NGL.GE
O61449_9ACAR QEPT.R......NLNGG................GA.......SNGVSS...........S.LLPQPS.......TYLSG.
O61448_9ACAR .M.ATQ.ER.APGLNGG..TS...........NG...........VSS...........S.LPPQPSLPAERLRRALGSI
HNF4A_MOUSE .............................................M...................D..........M.A.
HNF4A_RAT .............................................M...................D..........M.A.
Q6PHH5_BRARE .M...R.......L..S..K.............P............L............V.....D.....ME...M.A.
Q9JJI9_TAMSI .............................................M...................D..........M.A.
Q7YRQ5_BOVIN .............................................M...................D..........M.A.
HNF4A_HUMAN .............................................M...................D..........M.A.
Q5RH32_BRARE ESPR.I....Q..L.VS...A..D.........G.GL..QIVTEQQLAQKVQIVTAIDqgAGKQQFILANLDYPNQEKLF
Q7SZG3_FUGRU .M..............H..S.............I.........................S..SSEDI..........KPP
Q8AVK3_XENLA .M...R.......L..S..KA...........LI........D..M...................D..........M.A.
Q5QPB7_HUMAN .M...............................I......L.....LP.............LRL.ARLR...........
Q6IVK1_PLOIN .mp.............S...R.....E.....SG......L.N...LE...........N..STF......MSP..MSP.
Q95WF7_ACRMI .M.............AG............................VPA................QS..........WC..
Q6LDB2_9MURI ................................................................................
Q8AXB6_BRARE .M.....................................E.....M...................A..............
Q8I1M8_9NEOP .mp.............S...R.....E.....PG............L............NLEGSF......MSP..MSP.
O97120_SCHMA ssPSQQ...IYDML.DskSQTS.LKSSSCDTSNA.DLGVDIKphTVSSD.TNPNLCPinSINSThy.NTPQKFPHMLPP.
HNF4A_XENLA .M.............DM................A...........D...................Y..............
Q8JID3_CHICK .M.ATIEE.....L.AH..Q............IIEQQMGEI.THSQGA...........VTQTLMDG.........A.A.
Q6B4V6_HUMAN .M.............VS............................V.............NA.PLGAP...........V.
Q6B4V7_HUMAN .M.............VS............................V.............NA.PLGAP...........V.
Q6B4V5_HUMAN .M.............VS............................V.............NA.PLGAP...........V.
O96562_TRICY asSTAN.......DVVS..KEV...SEETK.LQIV...KEEETS.APsd..SSV.....SAMSKEGGLAMVDSC..LK.E
Q6ZMP8_HUMAN .M.F.R.........AG................A.............E...........GAE.KEP...........SP.
O46174_BOMMO .M...R..........S......DV.......LA......P.SE..LE...........G...TDY.L........LSST
O77099_AEDAE .M...K..........S................IVEVFCDY....DRSDF.........S.LGTS...........L.NI
Q26622_STRPU GMV............SS..QA...........TPV...EAYKVQQV.....QIN..DQTVEQ.LVRVQ......TSAGT.
Q8ST32_DIRIM .MDLCA.....SDWFASNltTPTSIDL...TQNG.dTTSRIGI.GDLEQ...PEEQFNHV.LNNYFHFSNPT.STTWFQQ
HNF4B_XENLA DMP.DY....TETL.DS..S....................Y.T..MLE................FDSIR......VLPS.
Q6PHZ7_HUMAN TSPSPR...IQIISTDS...AVASPQRI....QGSEPAskIVTDQQTGQKIQIVTAVDASGSPKQ..QFTLTSPDGAGTG
Q8I748_SUBDO .mv.DI....ST..YASPSSTPASSpe.....QIQMLDMELKPFemSSCKlpT..SPDpgMASYQSQQYMNDYKDPmpNT
O77100_AEDAE .M.............D.................I........N..Q.............N...NHD..........A.N.
Q8MLA0_DROME TSS.CRSIKKERIK.AS.QQAN.APPE.dVNIIIAAHSQRRRIGLvsEDR..PL....AVASplHSPQRHCYTPPPAppP
Q6P0E0_BRARE .M..KI.........SG..SS...................L....DLS...........V...TEYGIT.LD.PT..FTM
Q7YRQ4_BOVIN ................................................................................
Q9V7B3_DROME TSS.CRSIKKERIK.AS.QQAN.APPE.dVNIIIAAHSQRRRIGLvsEDR..PL....AVASplHSPQRHCYTPPPAppP
TR2_HUMAN .M.ATIEEI......AH..Q............IIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVI
Q15626_HUMAN .M.ATIEEI......AH..Q............IIEQQMGEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVI
NR2E3_HUMAN .M...E.............TR............P........TALM.............S....S...............
Q6DEH0_BRARE .............................................M.............S...KPAG...........S.
Q9U9R6_SCHMA FSETAAH.QSECSIVVSQLSTKKLT.......TPV.LCC.ISSNsqPSELCHIQpyIDSNCLSNQSNNDKSHSITPSSPL
O46175_BOMMO .............................................M.............G...LRD..............
NR2E1_ORYLA .M..............S.............................K...............PTGS..............
Q8JHW6_FUGRU .............................................M.............S...K.A..........AGS.
Q9Y1J4_SCHMA FSETAAH.QSECSIVVSQLSTKKLT.......TPV.LCC.ISSNsqPSELCHIQpyIDSNCLSNQSNNDKSHSITPSSPL
NR2E3_MOUSE .M.............SS...TV...........AA.......S.TMP............V.....SV...........A.
NR2E1_MOUSE .............................................M.............S...KPAG...........S.
HNF4G_MOUSE ................................................................................
Q7Z2V9_HUMAN ................................................................................
NR2E1_CHICK .............................................M.............S...KPAG...........S.
NR2E1_HUMAN .............................................M.............S...KPAG...........S.
HNF4G_HUMAN ................................................................................
Q8MX79_BRAFL .M...........................................M.............S..PNS.............V.
Q5U3F3_BRARE .M..............S............................M.............V...PFSS..........PT.
Q90WV5_CHICK .M.............A.................A.........................S....PA..............
NR2E1_XENLA .............................................MS............N..PTGS..............
NHR64_CAEEL .M...IF...FQNF.DH...TK.LK.......IPKNQ..FL.SKFQLF..............PTHFPFF..DSKTVLFS.
Q7YTB9_SACKO .............................................M.............N...KTA............T.
Q8IPT4_DROME .M.............DG............................VK............V..ETF.I..........KS.
Q9VP28_DROME .M.............DG............................VK............V..ETF.I..........KS.
HR78_DROME .M.............DG............................VK............V..ETF.I..........KS.
TLL_DROVI .M...........................................QS............S.EGSPD.....M....M...
TLL_DROME .M...........................................QS............S.EGSPD.....M....M...
Q9NCL0_TRICA .M..............S......................E.....M..................QSV.............
Q9VML1_DROME ................................................................................
O96680_DROME ................................................................................
Q5U7E0_MUSDO .M.................QT.........................TE...........G...SPDI.........M...
Q86PK5_CAEEL ................................................................................
Q61WY2_CAEBR .............................................MTP...........V.....D...........K..
P90892_CAEEL .MS.DE...DEP.LNFS..TSK...........ATEESKE.GILGVRS.........IFNTPLLFPPPMFNAGVISPH.I
Q8IVZ9_HUMAN ................................................................................
Q688B5_CAEEL .M...............................I.........FFQ.............N....FD..............
O77101_AEDAE ................................................................................
Q86PK4_CAEEL ................................................................................
D010 D020
|=========|======
CONSENSUS AAPGGGNAPELRKLTTGATSLNSSNSIKDPSGSDGGPKDKAQGPAGSPLLLHEPCAVCGDRSSGKHYGVYSCEGCKGFFK
RXRA_RAT TTPTLGFETGSPQLNSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMSSFTKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRA_MOUSE TTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRA_HUMAN TTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRB_HUMAN A.pfSGPVSSPQINSTVSLPGGGSGP.PEDVKPpgVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFK
Q5TJF7_CANFA apGFSGPVSSPQINSTVSLPGGGSGP.PEDVKplGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFK
RXRB_MOUSE apGFSGPVSSPQINSTVSLPGGGSGP.PEDVKPpgVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFK
Q6LC96_MOUSE TTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFK
Q6MGB3_RAT PG.FSGPVSSPQINSTVSLPGGGSGP.PEDVK.PPVLGV.cPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFK
RXRG_MOUSE AAPPGInaPPSSQLNVVN.SVSSSEDIKP.LPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRG_HUMAN PGI.NLVAPPSSQLNVVN.SVSSSEDIKP.LPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFK
Q5REL6_PONPY PGI.NLVAPPSSQLNVVN.SVSSSEDIKP.LPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRA_XENLA PGLGYGT.GSPQIHSP.MNSVSSTEDIKPPPGINGILKVPMHPSGAMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFK
7UP1_DROME DMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFK
RXRG_CHICK A.PGMNFVTHSPQPNVLN.NVSSSEDIKP.LPGLPGIGNMNYPSTSPGSLAKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRB_BRARE PSVGYGPISSPQINSTVSMSGLHAVSSSDDVKPPFGLKPLSSHSPGPMVSQKRLCAICGDRSSGKHYGVYSCEGCKGFFK
Q6INZ0_XENLA PSIGYGPVSSPQINSTVNLSGLHHVGSSEDVKPPLGMRSMQSHPNGGTVSGKRLCAICGDRSSGKHYGVHSCEGCKGFFK
Q91613_XENLA PSIGYGPVSSPQINSTVNLSGLHHVGSSEDVKPPLGMRSMQSHPNGGTVSGKRLCAICGDRSSGKHYGVHSCEGCKGFFK
RXRG_XENLA .TILNYPGHESPPFNILN.NVSCSEDIKPPPGLSSLGSPCMnsCNSPGALTKHICAICGDRSSGKHYGVYSCEGCKGFFK
RXRA_BRARE SMPTTSNMGYGALNSPQMNSLNSV.SSSEDIKPpgLAGLGSYPCGSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFK
Q86GV5_BRAFL QT.QQSTPGPQQP.GPPtpNGGSMPQQTPTAPTQPsqGQQQSTPTSGGQSQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
COT1_MOUSE AArgGGGAGEQQQAGSGAPHTPQTPGQPGAPATPGTQGDKGQGPPGsqSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
COT1_HUMAN AArgGGGAGeqQQAGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGsqSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
COT1_BOVIN AArgGGGAGeqQQAGSGAPHTPQTPGQPGAPATPGTAGDKGQGPPGsqSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q62681_RAT AAR.GGGGGEQQQAGSGAPHTPQTPGQPGAPATPGTAGDKGqpPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q9BMU6_AEDAE S...QHNAGSLAV..SQHTSVDKKEFLSLQQSTTPG.SQSMNSQNGSqkNQNIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q6DHP9_BRARE STPSMGFNT...LNSPQMNSLsgNEDIKPPPGLAPLGNMSSYQCTSPGSLSKHICAICGDRSSGKHYGVYSCEGCKGFFK
COT2_BOVIN ........PPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
COT2_HUMAN ........PPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
COT2_MOUSE ........PPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
COT2_RAT ........PPGAPHTPQTPGQGGPASTPAQTAAGSQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
NR2F1_BRARE P......AREQQQAASAAPHTPQTPSQPGPPSTPGTAGDKG.SQNSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q91430_BRARE L...GLTASQVAPPTPQT.PVQGPPNNNNNTQSTPTNQ.TTQSQSEKQQPQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q6PHF2_BRARE P......AREQQQAASAAPHTPQTPSQPGPPSTPGTAGDKG.SQNSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q9W745_XENLA ........REQQQAPSAAPHTPQTPSQPGPPSTPGAAGDKGQQGSGQSQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q91840_XENLA PSIGYGPVSSPQINSTVNLSGLHSVSSSEDVKPPLGMRSMPSHPNGGAVSGKRLCAICGDRSSGKHYGVYSCEGCKGFFK
Q8T5C6_BIOGL PS.....PGPQQMHSPGMHSPTSSMGSPPMLCLSPSGPSPSPGLPHSSLHTKHICAICGDRASGKHYGVYSCEGCKGFFK
COT2_CHICK ......GPPAGTPHTPQTPGPGG....PPSTPAQSNAASQQSQGDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q8MX78_BRAFL PVISQLGPTPLQNVSPHMMNTP.LMVNTGQLTPPAQPLQSPRPSQTPMGLSKHICQICGDRASGKHYGVYSCEGCKGFFK
Q6DCH6_XENLA ........REQQQAPSAAPHTPQTPSQPGPPSTPGAAGDKT......GQSQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q8VCR0_MOUSE P......VSSPQINSTVSLPGGGSGP.PEDVKPPVLGVRgcPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFK
Q7ZXI7_XENLA ........T.GAPHTPQTPGQG.VPPTTPAQSNPSSQSSQN..QGEKQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q9PS79_9PIPI ........R..APHTPQTPGQG.VPPTTPAQSNPSSQSSQN..QGEKQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q8UUM6_ORYLA PSVGYGPISSPQINSTVSMSGLHTVSSSDDVKPPLGLKQLSSHSPGPMLSQKRLCSICGDRSSGKHYGVYSCEGCKGFFK
RXRD_BRARE PSIGYGPISNSQINSSMSVSRLHAVSSSDDVKPPFGLKSV..SGSGPMLSQKRMCAICGDRSSGKHYGVYSCEGCKGFFK
Q66TQ0_9CAEN A......SPGGpmTSPQMHSPTSSLGSPTMMCLSPTGT.SSPGMPHSGLS.KHICAICGDRASGKHYGVYSCEGCKGFFK
Q6GN21_XENLA LARQDSNQGKVFLTTPDAAGMNQLFFSSPDVPAQHIqlSDTQSLDQNLNKqvELCVVCGDKASGRHYGAVTCEGCKGFFK
7UP2_DROME DMLPLIKGHGQDMLTSIKGQPTGCGSTTPSSQANSSHSQSSNSGSQIDSKQNIECVVCGDKSSGKHYGQFTCEGCKSFFK
Q6V7U7_LOCMI ......NSPGSF..TIG..HSSLLNN...SSSNQAKGSSSQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q66J63_XENLA LARQDSSQGKVFLTTPDAAGVNQLFFSTPDVPAQHIqlSDTQSLDQNLNKQFvlCVVCGDKASGRHYGAVTCEGCKGFFK
O76241_UCAPU ASP..SISTPPF..TIGSSNTTGL.STSPSQYPPSHPLSGSKHLCHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q8IPF2_DROME NGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFR
Q91720_XENLA D.......PGG...TPQTPTTP.KGGIPGQ...DPV.....HSGDKGVP..NVDCLVCGDKSSGKHYGQFTCEGCKSFFK
Q5RCZ5_PONPY LARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLtnSSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFK
Q95K90_MACFA LARQDSTPGKVFL.TPDAAGVNQLFFTTPDLSAQHLQLldNSSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFK
RXRG_BRARE ........T.VQL.SSPMNAVSSSEDIKPPLGLNGVMKVPAhiGTLSLSLTKHICAICGDRSSGKHYGVYSCEGCKGFFK
Q15625_HUMAN LARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFK
Q9VLI7_DROME NGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFR
NR2F5_BRARE .......EPGG...TPGTPSGS.....TP..GNDAL......SGDKIPN...VDCMVCGDKSSGKHYGQFTCEGCKSFFK
Q9GSG8_AEDAE QV...AAALQQQQQNVNSLNSQQSGGGGGAGGGtpTNMSQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
USP_MANSE LDIQWLNIEPGFM..SPMSPPEMKPDTadGLRDDStpAFKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
USP_CHOFU DM.QWLNLEPGFM..SPMSPPEMKPD.TAMLdaTSPPNFKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q6PH18_BRARE ........EELAAVdsAA.GREHLQHRH.SPKS...AEEKAQIAAQ..NQQHVECVVCGDKSSGKHYGQFTCEGCKSFFK
TR4_HUMAN KVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKTDVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFK
TR4_MOUSE KVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKADVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFK
Q6P0E6_BRARE ........EELAAVdsAA.GREHLQHRH.SPKS...AEEKAQIAAQ..NQQHVECVVCGDKSSGKHYGQFTCEGCKSFFK
TR4_RAT KVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKADVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFK
Q9U3Y3_AEDAL QV...AAAPQQQQQNVNN.SLNsgGGGGGGTPTTPTNMSQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q9GSG7_AEDAE QV...AAALQQQQQNVNSLNsgGGGGGGGGTPTTPTNMSQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q9U7D9_LOCMI ......NSPGSF..TIG..HSSLLNN...SSSNQAKGSSSQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
USP_BOMMO LDIQWLNIESGFM..SPMSPPEMKPD.TAMLdsTPPPPFKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q8VIJ3_MOUSE P.......GKVFLTTPDAAGVNQLFFTSPDLSAPHLQLLTENSPDQGPNKVFDLCVVCGDKASGRHYGAITCEGCKGFFK
Q8VIJ4_RAT P.......GKVFLTTPDAAGVNQLFFASPDLSTPHLQLLTENSPDQGPNKVFDLCVVCGDKASGRHYGAITCEGCKGFFK
EAR2_HUMAN .......GGYPRA....A...E......DDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFK
HNF4_DROME NGNAGSAGGGSASSGSNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFR
Q9NG48_APIME ....GNFSPSGP.NSPGSfhSNLL.STSPSGQNKAVAP...YPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q62152_MOUSE P.......GKVFLTTPDAAGVNQLFFTSPDLSAPHLQLLTEKSPDQGPNKVFDLCVVCGDKASGRHYGAITCEGCKGFFK
Q6GL59_XENTR ........GKGYPRNS.....E.EE...EA.SPQGGMSDP.EQGDEERPGIQVDCVVCGDKSSGKHYGVFTCEGCKSFFK
Q7T0T7_XENLA ........GKGYPRNS.....E.EE...EA.SPQGGMSDP.EQGDEERPGIQVDCVVCGDKSSGKHYGVFTCEGCKSFFK
Q922G8_MOUSE ......GGSYPRA..T.....E......DDSASPPGATSDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFK
Q9NFY1_TENMO ASTLGQNSPVSFASGHGSL.LSFSP.QGPPSGGTP.NKSCGspPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
EAR2_MOUSE ......GGSYPRA..T.....E......DDSASPPGATSDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFK
Q6P117_BRARE ........GYLR.......GDE......DDGSPQGGGSDME..AGEDDKGCVVDCVVCGDKSSGKHYGVFTCEGCKSFFK
EAR2_RAT ......GGSYPRA..T.....E......DDSASPPGATSDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFK
USP_DROME AMSMVHVLPGSNSASSNN.NsaQAPNSAGGSAAAAV..QQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
O45117_CHITE GANTFSPipSSPLSSIGnsPSNASSSSTLSGPLTTtgKQSQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q8CFY1_MOUSE ........DYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNSSNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q5QPB8_HUMAN ........DYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q962I5_LUCCU FA.....IGLQAINAVAAAN...ANNQNQMLQTTP.PQQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q6P115_BRARE K.......GYLR........GE.E....EGSSPQAGNSDVE..GGEEDKACVVDCVVCGDKSSGKHYGVFTCEGCKSFFK
O61449_9ACAR .......GGYGGTLSVNRagQPTL..SNGPSSATAPGGDSRFPATHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
O61448_9ACAR ........TVGRPAAQQR.SSGDT..ATAAAATSHHALST..KP..PLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
HNF4A_MOUSE ........DYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNSSNSLSVSALCAICGDRATGKHYGASSCDGCKGFFR
HNF4A_RAT ........DYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNSSNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q6PHH5_BRARE ........DYSEALDPAYTTLEFENMQVLAMSTDSSPQESANMNAANHLGAGTLCAICGDRATGKHYGASSCDGCKGFFR
Q9JJI9_TAMSI ........DYSAALDPAYTTLEFENVQVLAMGNDTSPSEGTNLAAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q7YRQ5_BOVIN ........DYSAALDPAYTTLEFENVQVLTMGNDTSPSEGANLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
HNF4A_HUMAN ........DYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q5RH32_BRARE IKQENSPA.KVILTSSDGSAVNQLLFASPELSGQQIQFVTD.GSDQGskPPVEYCVVCGDKASGRHYGAVSCEGCKGFFK
Q7SZG3_FUGRU F........GLRP..VPA.H............SPGLMM...........SQKRMCVICGDRSSGKHYGVYSCEGCKGFFK
Q8AVK3_XENLA ........DYTEALDPAYTTLEFENMQVLSIGTDTSTSDVTSLSASNSIGINSLCAICGDRATGKHYGASSCDGCKGFFR
Q5QPB7_HUMAN ........HPLRHHWSI..SGG..VDSSP..QGDTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q6IVK1_PLOIN ........PEM.KPDTAM..LDGLRD..DATSPPS...FKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
Q95WF7_ACRMI ........TE..K..TE..PLE......E..SA.....EK........NVQQVECAVCGDKSSGKHYGVFTCEGCKSFFK
Q6LDB2_9MURI .......................................MNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFK
Q8AXB6_BRARE ........DYSEALDPAYTTLEFENMQVLAMSTDSSPQESANMNAANHLGAGTLCAICGDRATGKHYGASSCDGCKGFFR
Q8I1M8_9NEOP ........PEM.KPDTAMLDV..LRD..DATSPPS...FKNYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFK
O97120_SCHMA DAHqdNVVSEprLLASGntSTSYLP.QvesLtsQSptQNPSELASQSSSATSviCVICGDKASGKHYGVISCEGCKGFFK
HNF4A_XENLA ........TE.AL.DPAYTTLEFENMQVLSIGTDTSTSDVTSLSASNSIGINSLCAICGDRATGKHYGASSCDGCKGFFR
Q8JID3_CHICK ..........QRIQ.IV.PSDSG.....LSLP.QRIQILTDNSSNEqlNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFK
Q6B4V6_HUMAN .........ES....S.Y...............DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q6B4V7_HUMAN .........ES....S.Y...............DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
Q6B4V5_HUMAN .........ES....S.Y...............DTSPSEGTNLNAPNSLGVSALCAICGDRATGKHYGASSCDGCKGFFR
O96562_TRICY ASPLESIHPYSPL.ASDA.SGSST...SPI.ASSSLLQLPSLTADSQRP.VQ.PCSVCSDKAYVKHYGVFACEGCKGFFK
Q6ZMP8_HUMAN ..R.....PECRA.DPG.PGLGF....PLGSGL.PWPSLLE..SPGGRIL.DIPCKVCGDRSSGKHYGVYACDGCSGFFK
O46174_BOMMO .MR..LEDSFLQILDSDM.QLE.T.SSSEASAASST...........TISQH..CAICGDRATGKHYGASSCDGCKGFFR
O77099_AEDAE .......EDTLfiLDHDANDSLSPTHTSEstPEQSVDSNKNYTLDNCQSSANNLCTICSDRATGKHYGAASCDGCKGFFR
Q26622_STRPU ........T.V..TTIDAATAERleD..LI.KFSAQGMSQAQMMAKpsPRPIELCAVCGDKASGRHYGAISCEGCKGFFK
Q8ST32_DIRIM EQMLPSN.TqlRP.ITDR.SQEFT.VSNDEVSSTTpaSQKSSTSMNVGTITKHICAICGDRASGKHYGVYSCEGCKGFFK
HNF4B_XENLA .......NTE..I..I...TVE........TASPGL......LN....NGINSFCAICGDRATGKHYGASSCDGCKGFFR
Q6PHZ7_HUMAN KVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKTDVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFK
Q8I748_SUBDO AAPPHYCADNRYMHNGVEpnYGMINGSSFYFSNYPQSVEGMSPSGQNLSLQQTICKICGDTASGNHFGVQSCEACKSFFR
O77100_AEDAE ........DSL....SPTHTSE.SRFTPE....QSVDSNKNYTLDNCQSSANNLCTICSDRATGKHYGAASCDGCKGFFR
Q8MLA0_DROME TSTGVAPPTQPPPPHPAAPNVP..NGRLLsaAAQAAANSMNHSSAAEGSslGLICVVCGDTSSGKHYGILACNGCSGFFK
Q6P0E0_BRARE L....EF.DGLRVLPVQTDPL.........MPGHASASV...PVVVPQQSSMSLCAICADRATGKHYGASSCDGCKGFFR
Q7YRQ4_BOVIN ............MQ.ILY.N...........SNDSSVPETTSMNTA.DNGVNCLCAICGDRATGKHYGASSCDGCKGFFR
Q9V7B3_DROME TSTGVAPPTQPPPPHPAAPNVP..NGRLLsaAAQAAANSMNHSSAAEGSslGLICVVCGDTSSGKHYGILACNGCSGFFK
TR2_HUMAN LARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFK
Q15626_HUMAN LARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRHYGAVTCEGCKGFFK
NR2E3_HUMAN ........T.VAAAAPAA....GAASRKESPGRWGL.GED...PTGVSPSLQ..CRVCGDSSSGKHYGIYACNGCSGFFK
Q6DEH0_BRARE ........TSGCL.DI....LN........VKS.............SRIL.DIPCKVCGDRSSGKHYGVYACDGCSGFFK
Q9U9R6_SCHMA LTNCNSPSTTLQSSTVCCLLRPSGRSTSTSSGSSCGSSCSGTGGGVSVSSGQYICSICSDRASGKHYGVFSCEGCKGFFK
O46175_BOMMO ........S.....DSDM.QLE.T.SSSEASAASST...........TISQH..CAICGDRATGKHYGASSCDGCKGFFR
NR2E1_ORYLA ........TSGCL.DI....LN........VKS.............SRIL.DIPCKVCGDRSSGKHYGVYACDGCSGFFK
Q8JHW6_FUGRU ........TSGCL.DI....LN........VKS.............SRIL.DIPCKVCGDRSSGKHYGVYACDGCSGFFK
Q9Y1J4_SCHMA LTNCNSPSTTLQSSTVCCLLRPSGRSTSTSSGSSCGSSCSGTGGGVSVSSGQYICSICSDRASGKHYGVFSCEGCKGFFK
NR2E3_MOUSE .......ASK..KESPGRWGLG......ED..PTGV...........GPSLQ..CRVCGDSSSGKHYGIYACNGCSGFFK
NR2E1_MOUSE ........T.SRILDI.....................................PCKVCGDRSSGKHYGVYACDGCSGFFK
HNF4G_MOUSE ............MNTTD...............................SGVNCLCAICGDRATGKHYGASSCDGCKGFFR
Q7Z2V9_HUMAN ............MNTTD...............................NGVNCLCAICGDRATGKHYGASSCDGCKGFFR
NR2E1_CHICK ........T.SRILDI.....................................PCKVCGDRSSGKHYGVYACDGCSGFFK
NR2E1_HUMAN ........T.SRILDI.....................................PCKVCGDRSSGKHYGVYACDGCSGFFK
HNF4G_HUMAN ............MNTTD...............................NGVNCLCAICGDRATGKHYGASTCDGCKGFFR
Q8MX79_BRAFL ..........LF..TPG..............SGDT..............KPQELCVVCGDKASGRHYGAISCEGCKGFFK
Q5U3F3_BRARE ........ESSRSNSTD........D.SQDGKSPAPGKV...LNTG...L...LCKVCSDTSSGKHYGIYACNGCSGFFK
Q90WV5_CHICK ........G.....SVVSAGLE......D..SPSGL.....SPAPGKALSPVLLCKVCGDTSSGKHYGIYACNGCSGFFK
NR2E1_XENLA ........T.SRILDI.....................................PCKVCGDRSSGKHYGVYACDGCSGFFK
NHR64_CAEEL ........EE..M..T....LE.E...KEEVSTSTS......QSPQSSSFENVFCAICGDRATGKHYGAMSCDGCKGFFR
Q7YTB9_SACKO ........TSSRILDI.....................................PCKVCGDRSSGKHYGVYACDGCSGFFK
Q8IPT4_DROME ........EENrmPLIG..GGSASGGTPLP.GG.GVGM....GAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFK
Q9VP28_DROME ........EENrmPLIG..GGSASGGTPLP.GG.GVGM....GAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFK
HR78_DROME ........EENrmPLIG..GGSASGGTPLP.GG.GVGM....GAGASATLSVELCLVCGDRASGRHYGAISCEGCKGFFK
TLL_DROVI ........D..QKYNSVRLS......................PAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFK
TLL_DROME ........D..QKYNSVRLS......................PAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFK
Q9NCL0_TRICA .........EGAM..V..HHLE..PHRMQI.KPQS.......PSSSSRIL.DIPCKVCGDFSSGKHYNIFACDGCAGFFK
Q9VML1_DROME ..........................................MGTAGDRLLDIPCKVCGDRSSGKHYGIYSCDGCSGFFK
O96680_DROME ..........................................MGTAGDRLLDIPCKVCGDRSSGKHYGIYSCDGCSGFFK
Q5U7E0_MUSDO ........D..QKYNSVRLS......................PAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFK
Q86PK5_CAEEL ............M..T....LE.E...KEEVSTSTS......QSPQSSSFENVFCAICGDRATGKHYGAMSCDGCKGFFR
Q61WY2_CAEBR ........EEPA..TS...............STS.......QSPN...SFENVFCAICGDKATGKHYGALSCDGCKGFFR
P90892_CAEEL AA..ALAMsqQRMNASVSPPLDHTTISVNSFPSMGSVK.TDSPPTASSPTLC..CAVCGDVSSGKHYGILACNGCSGFFK
Q8IVZ9_HUMAN ................................................................................
Q688B5_CAEEL .......HTKL.K..IPK.NQ.FL..SKFQLFPTHFPFFD..SKTV..LFSEEMTLEEKEEVSTSTSQSPQSSSFENVFC
O77101_AEDAE ................................................................................
Q86PK4_CAEEL .....................................................MTLEEKEEVSTSTSQSPQSSSFENVFC
D030 D040 D050 D060 140 150
===|=========|=========|=========|====== ===|=========|=
CONSENSUS RSVRKNLTYTCRSNRDCPIDKHHRNQCQYCRLKKCLAVGMNRDAVQEERDPSKQTGPNDSAPTTAAYLSMPIELLLRAEP
RXRA_RAT RTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAEL
RXRA_MOUSE RTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAEL
RXRA_HUMAN RTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
RXRB_HUMAN RTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD.GDGEGAGGAPEEMPVDRILEAEL
Q5TJF7_CANFA RTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD.GDGEGAGGAPEEMPVDRILEAEL
RXRB_MOUSE RTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD.GDGDGAGGAPEEMPVDRILEAEL
Q6LC96_MOUSE RTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKILEAEL
Q6MGB3_RAT RTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD.GDGDGAGGAPEEMPVDRILEAEL
RXRG_MOUSE RTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERILEAEL
RXRG_HUMAN RTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAEL
Q5REL6_PONPY RTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSGHEDMPVERILEAEL
RXRA_XENLA RTVRKDLTYTCRDSKDCMIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKERNENEVESSNSANEDMPVEKILEAEH
7UP1_DROME RSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMhfNGHSYLSSYISLLLRAEP
RXRG_CHICK RTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQGSRERSENEAESTSGGSEDMPVERILEAEL
RXRB_BRARE RTVRKDLSYTCRDNKDCLVDKRQRNRCQYCRYQKCLAMGMKResVQEERQRNKERD.GEVESSSAANEEMPVEKILEAEM
Q6INZ0_XENLA RTIRKDLTYTCRDSKDCIVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGRERD.GEAELSGAINEEMPVEKILEAEL
Q91613_XENLA RTIRKDLTYTCRDSKDCIVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGRERD.GEAELSGAINEEMPVEKILEAEL
RXRG_XENLA RTIRKDLVYTCRDSKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRSREKSDTEAESTSSTSEEMPVERILEAEL
RXRA_BRARE RTIRKDLTYTCRDNKDCQIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGRERSDNEVDSSSSFNEEMPVEKILDAEL
Q86GV5_BRAFL RSVRRNLTYSCRGNRTCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRIPPTqpAGAQYaiNGHSYLSGYISLLLRAEP
COT1_MOUSE RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
COT1_HUMAN RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
COT1_BOVIN RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
Q62681_RAT RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
Q9BMU6_AEDAE RSVRRNLTYSCRGNRNCPIDQHHRNQCQFCRLRKCLKMGMRREAVQRGRVPPSqsIPNGDafNGHSYLSSYISLLLRAEP
Q6DHP9_BRARE RTIRKDLTYTCRDIKECLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKEKSDTEVETTSRFNEDMPVDKILDAEL
COT2_BOVIN RSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPSHGQFALTnhSYLSGYISLLLRAEP
COT2_HUMAN RSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFalNCHSYLSGYISLLLRAEP
COT2_MOUSE RSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFalNCHSYLSGYISLLLRAEP
COT2_RAT RSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFalNCHSYLSGYISLLLRAEP
NR2F1_BRARE RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
Q91430_BRARE RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPHHGQFALTNgsYLSGYISLLLRAEP
Q6PHF2_BRARE RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRRE.VQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
Q9W745_XENLA RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
Q91840_XENLA RTIRKDLTYTCRDSKDCIVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKERD.GEAELSGAINEEMPVEKILEAEL
Q8T5C6_BIOGL RTVRKDLTYACRDDKNCMIDKRQRNRCQYCRYMKCLSMGMKREAVQEERQRVKEKGDGEVESTSGANNDMPVEQILEAEL
COT2_CHICK RSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFalNCHSYLSGYISLLLRAEP
Q8MX78_BRAFL RTVRKDLTYACRDNRDCVIDKRQRNRCQYCRYQKCLAMGMKReaVQEERQRSKEGKDGEVVSTTNPNEDMPVEKIQEAEM
Q6DCH6_XENLA RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRFKKCLKVGMRRE.VQRGRMPPTQPNPGQYALTnhCYLSGYISLLLRAEP
Q8VCR0_MOUSE RTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD.GDGDGAGGAPEEMPVDRILEAEL
Q7ZXI7_XENLA RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFalNCHSYLSGYISLLLRAEP
Q9PS79_9PIPI RSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFalNCHSYLSGYISLVLRAEP
Q8UUM6_ORYLA RTVRKDLTYTCRDNKDCTVDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRNKER.EGEVESTSAVNEEMPVEKILEAEM
RXRD_BRARE RTVRKDLSYTCRDNKECLVDKRQRNRCQYCRYQKCLAMGMKREAVQEERQKNKERD.GDYECSSSANEEMPVEKILEAET
Q66TQ0_9CAEN RTVRKDLTYACRDDKNCMIDKRQRNRCQYCRYMKCLAQGMKREAVQEERQRVKEKGDGEVESTSGANSDMPVEQILEAEI
Q6GN21_XENLA RSIRKNLVYTCRGSKDCVINKHYRNRCQYCRLQRCMSLGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
7UP2_DROME RSVRRNLTYSCRGSRNCPIDQHHRNQCQYCRLKKCLKMGMRREAVQRGRVPPTQPGLAGMhfNGHSYLSSYISLLLRAEP
Q6V7U7_LOCMI RTVRKDLSYACREDKNCIIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRTKERDQNEVESTSSLHTDMPVERILEAEK
Q66J63_XENLA RSIRKNLIYTCRGSKDCVINKHYRNRCQYCRLQRCISLGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
O76241_UCAPU RTVRKDLTYACREERSCTIDKRQRNRCQYCRYQKCLTMGMKREAVQEERQRTkdKGDGDTESSCGAISDMPIASIREAEL
Q8IPF2_DROME RSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPD..PGNGLSVISLVKAEN
Q91720_XENLA RSVRRNLTYTCRSNRDCPIDQHHRNQCQYCRLKKCLKVGMRRE.VQRGRMSHPQTSPGQYTLngHSYLTGFISLLLRAEP
Q5RCZ5_PONPY RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
Q95K90_MACFA RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
RXRG_BRARE RTVRKDLTYTCRDNKDCMIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRAKERSEAEFGG.C.ANEDMPVEKILEAEL
Q15625_HUMAN RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
Q9VLI7_DROME RSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPD..PGNGLSVISLVKAEN
NR2F5_BRARE RSVRRNLSYTCRGNRDCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMSNSQSSPGQYLsnGQPYLSGFISLLLRAEP
Q9GSG8_AEDAE RTVRKDLSYACREDKNCTIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRSSKFSIKSEEIntSSVRDVTIERIHEAEQ
USP_MANSE RTVRKDLTYACREDRNCIIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRAA.RGTEDAHPSS.SVQELSIERLLEIES
USP_CHOFU RTVRKDLSYACREERNCIIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRNA.RGAEDAHpsVQVSDELSIERLTEMES
Q6PH18_BRARE RSVRRNLSYTCRANRNCPVDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPNQPNPSHYALTnqCYLSGYISLLLRAEP
TR4_HUMAN RSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCA.ASTEKIYIRKDLRSPL
TR4_MOUSE RSVRKNLTYSCRSSQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCA.ASTEKIYIRKDLRSPL
Q6P0E6_BRARE RSVRRNLSYTCRANRNCPVDQHHRNQCQYCRLKKCLKVGMRRE.VQRGRMPPNQPNPSHYALTnqCYLSGYISLLLRAEP
TR4_RAT RSVRKNLTYSCRSSQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCA.ASTEKIYIRKDLRSPL
Q9U3Y3_AEDAL RTVRKDLSYACREDKNCTIDKRQRNRCLYCRYQKCLACGMKREAVQEERQRSSKFSIKSEEIntSSVRDVTIERITAAEQ
Q9GSG7_AEDAE RTVRKDLSYACREDKNCTIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRSSKFSIKSEEIntSSVRDVTIERIHEAEQ
Q9U7D9_LOCMI RTVRKDLSYACREDKNCIIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRTKERDQNEVESTSSLHTDMPVERILEAEK
USP_BOMMO RTVRKDLTYACREDKNCIIDKRQRNRCQYCRYQKCLACGMKREAVQEERQRAA.RRTEDAHPSS.SVQELSIERLLELEA
Q8VIJ3_MOUSE RSIRKNLVYSCRGSKDCVINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKNLRSPL
Q8VIJ4_RAT RSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
EAR2_HUMAN RSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPG.AVAASspGQPVSELIAQLLRAEP
HNF4_DROME RSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTSNDDPD..PGNGLSVISLVKAEN
Q9NG48_APIME RTVRKDLSYACREEKSCIIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRTKERDQSEVESTSSLHSDMPIERILEAEK
Q62152_MOUSE RSIRKNLVYSCRGSKDCVMNKHHRNRCQYCRLQRCIAFGMKQDSVQCERKPIEVSREKSSNCA.ASTEKIYIRKDLRSPL
Q6GL59_XENTR RSVRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPPAHSSASP.TSanGQPVSELISQLLRAEP
Q7T0T7_XENLA RSVRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPPAHSSASP.TSanGQPVSELISQLLRAEP
Q922G8_MOUSE RSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHALPGPA..ACSpgPPVSELIAQLLRAEP
Q9NFY1_TENMO RTVRKDLSYACREEKNCIIDKRQRNRCQYCRYQKCLNMGMKREAVQEERQRTKDRDTSEVESTSNMQAEMPLDRIIEAEK
EAR2_MOUSE RTIRRNLSYTCR</