NucleaRDB: Point mutations extracted from the literature - ECR_DROME

logo    2005, NucleaRDB.

This data was extracted from medline abstracts and full text papers (when available) in an automated manner.

Each point mutation is linked to the entry specific to the residue position. Citations are linked to the list of point mutations found in the corresponding articles. The last column allows you to go back to the original text via Medline.

ProteinECR_DROME (EcR,NR1H1,CG176)Swiss-Prot
Cross-reference table
Family page
Protein isoforms3
Family alignments 1H1 Ecdysone
1H Ecdysone-like (ECR,LXR,FXR)
1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR

MutationLocationGeneral numberingReference
C300YDNA_BINDD037Gates J et al., Development 2004Medline
R344QHINGE Carney GE et al., Genetics 2000Medline
E476LBD HELIX 3348Grebe M et al., Biol Chem 2003Medline
A483TLoop 3-4 Carney GE et al., Genetics 2000Medline
K497LBD HELIX 4456Grebe M et al., Biol Chem 2003Medline
M504LBD HELIX 5552Grebe M et al., Biol Chem 2003Medline
R511LBD HELIX 5559Grebe M et al., Biol Chem 2003Medline
D572Loop 8-9 Grebe M et al., Biol Chem 2003Medline
A612LBD HELIX 10-111041Grebe M et al., Biol Chem 2003Medline
L615LBD HELIX 10-111044Grebe M et al., Biol Chem 2003Medline
I617LBD HELIX 10-111046Grebe M et al., Biol Chem 2003Medline
T619LBD HELIX 10-111048Grebe M et al., Biol Chem 2003Medline
N626LBD HELIX 10-111055Grebe M et al., Biol Chem 2003Medline
F645ALBD HELIX 121247Cherbas L et al., Development 2003Medline
F645ALBD HELIX 121247Hu X et al., Mol Endocrinol 2003Medline
E648LBD HELIX 121250Grebe M et al., Biol Chem 2003Medline
W650ALBD HELIX 121252Cherbas L et al., Development 2003Medline
W650ALBD HELIX 121252Hu X et al., Mol Endocrinol 2003Medline

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F.Horn (nucleardbcmbi.kun.nl), 21-Apr-2005