This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation F279A was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|Cited point mutation:||Phe279Ala,Phe279|
|Domain:||LBD HELIX 5|
|General numbering (NucleaRDB):||560|
|Other point mutations / same protein||List of mutations in VDR_HUMAN|
1I1 Vitamin D3 (VDR)|
1I Vitamin D3-like (VDR,PXR,CAR)
1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR
|Other point mutations / same position|
|Reference:||The importance of the putative helices 4 and 5 of human vitamin D(3) receptor for conformation and ligand binding.|
Vaisanen S, Duchier C, Rouvinen J, Maenpaa PH
Biochem Biophys Res Commun 1999 Oct 22;264(2):478-82.
|Other point mutations / same article||List|
|Validation status||True positive|