NucleaRDB: sequence-derived data

Information is available for the following families:

• Protein families
  • All the receptors of families 1 to 6
  • 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR
  • 2 HNF4-like (HNF4,RXR,TLL,COUP,USP)
  • 3 Estrogen like (ER,ERR,GR,MR,PR,AR)
  • 4 Nerve Growth factor IB-like (NGFIB,NURR)
  • 5 Fushi tarazu-F1 like (SF1,FTF,FTZ-F1)
  • 6 Germ cell nuclear factor like (GCNF1)
  • 0A Knirps like (KNI,KNRL,EGON,ODR7) (no LBD)
  • 0B DAX like (DAX,SHP) (no DBD)

• Non-classified:
  • Unclassified nuclear receptors

• Special clustering:
  • Human receptors

'Complete' list of families, sub-families, etc

• All the receptors of families 1 to 6

• 1 Thyroid hormone like (TR,RAR,ROR,PPAR,VDR

  • 1A Thyroid hormone (TR)
    • 1A1 Thyroid hormone alpha
    • 1A2 Thyroid hormone beta

  • 1B Retinoic acid (RAR)
    • 1B1 Retinoic acid alpha
    • 1B2 Retinoic acid beta
    • 1B3 Retinoic acid gamma
    • 1Bx Retinoic acid like

  • 1C Peroxisome proliferator activated (PPAR)
    • 1C1 PPAR alpha
    • 1C2 PPAR beta
    • 1C3 PPAR gamma

  • 1D REV-ERB (NRD1,NRD2,E75)
    • 1D1 REV-ERB alpha
    • 1D2 REV-ERB beta
    • 1D3 E75

  • 1E Ecdysone-inducible protein E78
    • 1E1 E78

  • 1F RAR-related orphan receptor (ROR,HR3)
    • 1F1 ROR alpha
    • 1F2 ROR beta
    • 1F3 ROR gamma
    • 1F4 HR3,CHR3

  • 1G CNR14
    • 1G1 CNR14

  • 1H Ecdysone-like (ECR,LXR,FXR)
    • 1H1 Ecdysone
    • 1H2 Oxysterol LXR beta
    • 1H3 Oxysterol LXR alpha
    • 1H4 Farnesoid FXR

  • 1I Vitamin D3-like (VDR,PXR,CAR)
    • 1I1 Vitamin D3 (VDR)
    • 1I2 Pregnane X (PXR)
    • 1I3 Constitutive Androstane alpha (CAR1)
    • 1I4 Constitutive Androstane beta (CAR2)

  • 1J DHR96
    • 1J1 DHR96

  • 1K NHR1
    • 1K1 NHR1

• 2 HNF4-like (HNF4,RXR,TLL,COUP,USP)

  • 2A Hepatocyte nuclear factor 4 (HNF4)
    • 2A1 HNF4 alpha
    • 2A2 HNF4 gamma
    • 2A3 HNF4 beta
    • 2A4 DHNF4
    • 2Ax HNF4 like

  • 2B Retinoic acid X (RXR,USP)
    • 2B1 RXR alpha
    • 2B2 RXR beta
    • 2B3 RXR gamma
    • 2B4 USP
    • 2Bx RXR other

  • 2C Orphan nuclear receptors TR2, TR4
    • 2C1 TR2
    • 2C2 TR4
    • 2Cx TR4-like

  • 2D DHR78
    • 2D1 DHR78

  • 2E Tailless-like (TLL,TLX,PNR,DSF,FAX)
    • 2E1 Tailless homolog (TLX)
    • 2E2 Tailless (TLL)
    • 2E3 Photoreceptor-specific (PNR)
    • 2E4 Dissatisfaction
    • 2E5 FAX-1
    • Photoreceptor-specific like

  • 2F COUP-TF-like (COUP-TF,SVP,EAR2)
    • 2F1 COUP-TFI
    • 2F2 COUP-TFII
    • 2F3 Seven-up (SVP)
    • 2F4 COUP-TFIII
    • 2F5 Seven-up related (SVP46)
    • 2F6 V-erbA related protein (EAR2)
    • 2F Other

• 3 Estrogen like (ER,ERR,GR,MR,PR,AR)

  • 3A Estrogen (ER)
    • 3A1 ER alpha
    • 3A2 ER beta

  • 3B Estrogen-related (ERR)
    • 3B1 ERR alpha
    • 3B2 ERR beta
    • 3B3 ERR gamma
    • 3B ERR other

  • 3C Glucocorticoid-like (GR,MR,PR,AR)
    • 3C1 Glucocorticoid (GR)
    • 3C2 Mineralocorticoid (MR)
    • 3C3 Progesterone (PR)
    • 3C4 Androgen (AR)

• 4 Nerve Growth factor IB-like (NGFIB,NURR)

  • 4A NGFI-B-like (NGFI-B, NURR,NOR,HR38,CNR-8)
    • 4A1 NGFI-B (HMR)
    • 4A2 NURR1
    • 4A3 NOR1
    • 4A4 DHR38
    • 4A5 CNR-8
    • 4Ax NR4A like

• 5 Fushi tarazu-F1 like (SF1,FTF,FTZ-F1)

  • 5A Fushi tarazu-F1 like (FTZ-F1,FTF,SF1)
    • 5A1 Steroidogenic factor-1 (SF1)
    • 5A2 Fetoprotein TF (LRH-1,FTF)
    • 5A3 Fushi tarazu-F1 (FTZ-F1)
    • 5A4 Fushi tarazu-F1 (FF1B)
    • 5A Other

  • 5B DHR39
    • 5B1 DHR39

  • 5 Other

• 6 Germ cell nuclear factor like (GCNF1)

  • 6A Germ cell nuclear factor (GCNF1)
    • 6A1 GCNF1

• 0A Knirps like (KNI,KNRL,EGON,ODR7) (no LBD)

  • 0A1 Knirps (KNI)

  • 0A2 Knirps-related (KNRL)

  • 0A3 Embryonic gonad protein (EGON)

  • 0A4 ODR-7

  • 0A5 Trithorax (TRX)

• 0B DAX like (DAX,SHP) (no DBD)

  • 0B1 DAX

  • 0B2 SHP

• Unclassified nuclear receptors

  • Vertebrate receptors

  • Nematode receptors

  • Insect receptors

  • Other receptors

• Human receptors

• Special clustering for SF1 mouse (RXR)

• Special clustering for SF1 mouse (ROR)

• Special clustering for COUP-TF1 human

F.Horn (nucleardbcmbi.kun.nl), 21-Apr-2005