Results of Nuclear Localization Signal Prediction(NLS):

  • Help on interpretation of results.


    • Input Sequence (NLS's in Red) 
    MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
LRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPPPDYMLPPGLHVPEPKGLASGPPAGPLGDFGAPALPMAVPSTNGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGPPYGYPEPFSGGPGVPELILQLLQLEPDEDQV
RARIIGCLQEPAKGRPDQPASFNLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSTLLVTGQEVELTTVAAQAGSLLHGLVLRAQELVLQMHA
LQLDRQEFVCLKFLILFSLDVKFLNNHSLVKDAQEKANTALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQ
    Sequence Length460
    NLS's found. No gives position of Motif
    • DKTLRKR 57

    Statistical data for Nuclear Localization Signals present in the Input Sequence

    Generalized NLS
    ( notation )    		 TypeNo with NLS%Nuc Proteins%NonNuc ProteinsProtein Swiss IdProtein Localizations(Swiss anno.)
    D[KR]x{0,1}[QL][RK]{2,3}R Potential 9 100 0 qin_avis3 nuc
    ftf1_drome nuc
    mam_drome nuc
    ceba_human nuc
    cg2f_human nuc
    ceba_mouse nuc
    rag1_mouse nuc
    ceba_rat nuc
    rpc8_yeast nuc

    Symbols used in representing the NLS are explained below:

    An x (or X) implies any amino acid residue can be present at this position.

    Example Motifs
    Example Read Equivalent Motifs
    [KR]KRKK "K or R" KRKK KKRKK,RKRKK
    K{5} 5 times K KKKKK
    [KR]{3,5} between 3 and 5 times K or R KKRR, RRKKR, RRR,KKK ...
    K{3,}? 3 or more K's KKK,KKKK,KKKKK ...