Results of Nuclear Localization Signal Prediction(NLS):

  • Help on interpretation of results.


    • Input Sequence (NLS's in Red) 
    MVDTQQLLAWPVGFSLSAVDLSELDDSSHSLDMKHLATLDYTSISSASVPSSLSPQLMSS
ISPVGMAYDPSPPQSEEHLTNMDYTNMHSYRTEPNVHNSIKMEPESPPQYSDSPVFSKLQ
DDPTAASLNIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLVYDHCDLHCRIHKKSR
NKCQYCRFQKCLNVGMSHNAIRFGRMPQAEKEKLLAEFSSDMEHMHPEAADLRALARHLY
EAYLKYFPLTKAKARAILSGKTGDNAPFVIHDMKSLMEGEQFINCRQMPIQEQQQASVLT
AAHGGLTEVHMGSDYGVWGMTSISGQEPQNALELRFFQSCQSPSAEAVREVTEFAKSIPG
FTDLDLNDQVTLLKYGVIEVLIIMMSPLMNKDGTLISYGQIFMTREFLKSLRKPFCQMME
PKFEFSVKFNTLELDDSDMALFLVVIILSGDRPGLLNVKPIEQLQETVLHSLELQLKLNH
PDSLQLFAKLLQKMTDLRQIVTDHVHLIQLLKKTEIDMCLHPLLQEIMKDLY
    Sequence Length532
    NLS's found. No gives position of Motif
    • KKSRNKC 176

    Statistical data for Nuclear Localization Signals present in the Input Sequence

    Generalized NLS
    ( notation )    		 TypeNo with NLS%Nuc Proteins%NonNuc ProteinsProtein Swiss IdProtein Localizations(Swiss anno.)
    KK[MNQSTC]R[MNQSTC]K[MNQSTC] Potential 12 100 0 ppar_cavpo nuc
    ppar_human nuc
    ppas_human nuc
    ppat_human nuc
    ppar_mouse nuc
    ppas_mouse nuc
    ppat_mouse nuc
    ppar_rat nuc
    ppat_rabit nuc
    ppar_xenla nuc
    ppas_xenla nuc
    ppat_xenla nuc

    This protein is predicted to bind to DNA.

    DNA Binding signals. KK[MNQSTC]R[MNQSTC]K[MNQSTC]

    DNA binding statistics for the binding NLS signals.

    DnaBindNLS No binding DNA %binding DNA No in binding Domain %in binding Domain % of associated DNA binding domains
    KK[MNQSTC]R[MNQSTC]K[MNQSTC] 12 100 12 100 ZINC FINGERS: 100

    Symbols used in representing the NLS are explained below:

    An x (or X) implies any amino acid residue can be present at this position.

    Example Motifs
    Example Read Equivalent Motifs
    [KR]KRKK "K or R" KRKK KKRKK,RKRKK
    K{5} 5 times K KKKKK
    [KR]{3,5} between 3 and 5 times K or R KKRR, RRKKR, RRR,KKK ...
    K{3,}? 3 or more K's KKK,KKKK,KKKKK ...