Results of Nuclear Localization Signal Prediction(NLS):

  • Help on interpretation of results.


    • Input Sequence (NLS's in Red) 
    MLVPPVSMIMYHELPSIKNKKREKIPEGTLCVVCSDFASGIHYSVASCNGCKTFFRRALV
NKQTFTCQFSGDCVVGKSVRCVCRSCRLKKCFDMGMDPKAIQHDRDKIRYTKALKKKREE
EKRLKEMVIKEDIGSPQSIASDTYINTSTPSSSTMINILENDHHSYDPEAQNDVKAVIED
LLRLESRVKSLRNSYRFESQVSATSCMYSSFLFFSCLLDDITYMAENTHENEGTIEPFEC
SVEKLREWFVRDLSLMLEWGKCLPIMERLLLNDKLALMKAFAPIFPLIQLAFYTRNEFEC
DIVIKLEPDCTPKPIPERLNYPDGSFIEKGNKPANTWEEMHTMLIDGCYKMMRQLKIKES
TFVLYKMLLFHNPDADGLSSLGKKTIENERMRLLTQLFSYLSTERGKEAQTIFSNLLMMS
ATLSKTASFIKRVFDFNHIFNRTNDLIDQLIIVGL
    Sequence Length455
    NLS's found. No gives position of Motif
    • KKKREEEKRLK 114

    Statistical data for Nuclear Localization Signals present in the Input Sequence

    Generalized NLS
    ( notation )    		 TypeNo with NLS%Nuc Proteins%NonNuc ProteinsProtein Swiss IdProtein Localizations(Swiss anno.)
    KKxRx{3,5}R[PVL]K Potential 4 100 0 dpoa_human nuc
    dpoa_mouse nuc
    dpoa_rat nuc
    ly14_yeast nuc

    Symbols used in representing the NLS are explained below:

    An x (or X) implies any amino acid residue can be present at this position.

    Example Motifs
    Example Read Equivalent Motifs
    [KR]KRKK "K or R" KRKK KKRKK,RKRKK
    K{5} 5 times K KKKKK
    [KR]{3,5} between 3 and 5 times K or R KKRR, RRKKR, RRR,KKK ...
    K{3,}? 3 or more K's KKK,KKKK,KKKKK ...