Swiss-Prot entry

ID   Q6X2Y2_HUMAN PRELIMINARY;      PRT;   580 AA.
AC   Q6X2Y2;
DT   05-JUL-2004 (TrEMBLrel. 27, Created)
DT   05-JUL-2004 (TrEMBLrel. 27, Last sequence update)
DT   05-JUL-2004 (TrEMBLrel. 27, Last annotation update)
DE   Small-conductance calcium-activated potassium channel SK2.
GN   Name=SK2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; 
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. 
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Heart;
RX   PubMed=13679367 [NCBI, ExPASy, EBI, Israel, Japan]; DOI=10.1074/jbc.M307508200;
RA   Xu Y., Tuteja D., Zhang Z., Xu D., Zhang Y., Rodriguez J., Nie L.,
RA   Tuxson H.R., Young J.N., Glatter K.A., Vazquez A.E., Yamoah E.N.,
RA   Chiamvimonvat N.;
RT   "Molecular identification and functional roles of a Ca2+-activated K+
RT   channel in human and mouse hearts.";
RL   J. Biol. Chem. 278:49085-49094(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Heart;
RA   Tuteja D., Zhang Z., Xu Y., Sharma D., Rodriguez J., Nie L.P.,
RA   Tuxson H., Young N., Glatter K.A., Vazquez A.E., Chiamvimonvat N.;
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
DR   EMBL; AY258141; AAP45946.1; -. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   HSSP; P70604; 1KKD. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
DR   GO; GO:0016021; C:integral to membrane; IEA.
DR   GO; GO:0005516; F:calmodulin binding; IEA.
DR   GO; GO:0005216; F:ion channel activity; IEA.
DR   GO; GO:0016286; F:small conductance calcium-activated potassi...; IEA.
DR   GO; GO:0006811; P:ion transport; IEA.
DR   GO; GO:0006813; P:potassium ion transport; IEA.
DR   InterPro; IPR004178; CaMBD.
DR   InterPro; IPR001622; K+channel_pore.
DR   InterPro; IPR003931; SK_channel.
DR   InterPro; Graphical view of domain structure.
DR   Pfam; PF02888; CaMBD; 1.
DR   Pfam; Graphical view of domain structure.
DR   PRINTS; PR01451; SKCHANNEL.
DR   CMR; Q6X2Y2.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain]
DR   HOVERGEN [Family / Alignment / Tree]
DR   ProtoMap; Q6X2Y2.
DR   PRESAGE; Q6X2Y2.
DR   ModBase; Q6X2Y2.
DR   SMR; Q6X2Y2.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   Ionic channel.
SQ   SEQUENCE   580 AA;  63858 MW;  E6DE0CDF1A3F0E4E CRC64;
     MSSCRYNGGV MRPLSNLSAS RRNLHEMDSE AQPLQPPASV GGGGGASSPS AAAAAAAAAV
     SSSAPEIVVS KPEHNNSNNL ALYGTGGGGS TGGGGGGGGS GHGSSSGTKS SKKKNQNIGY
     KLGHRRALFE KRKRLSDYAL IFGMFGIVVM VIETELSWGA YDKASLYSLA LKCLISLSTI
     ILLGLIIVYH AREIQLFMVD NGADDWRIAM TYERIFFICL EILVCAIHPI PGNYTFTWTA
     RLAFSYAPST TTADVDIILS IPMFLRLYLI ARVMLLHSKL FTDASSRSIG ALNKINFNTR
     FVMKTLMTIC PGTVLLVFSI SLWIIAAWTV RACERYHDQQ DVTSNFLGAM WLISITFLSI
     GYGDMVPNTY CGKGVCLLTG IMGAGCTALV VAVVARKLEL TKAEKHVHNF MMDTQLTKRV
     KNAAANVLRE TWLIYKNTKL VKKIDHAKVR KHQRKFLQAI HQLRSVKMEQ RKLNDQANTL
     VDLAKTQNIM YDMISDLNER SEDFEKRIVT LETKLETLIG SIHALPGLIS RTIRQQQRDF
     IEAQMESYDK HVTYNAERSR SSSRRRRSSS TAPPTSSESS
//