Swiss-Prot entry

ID   Q5HZV4_XENTR PRELIMINARY;      PRT;   330 AA.
AC   Q5HZV4;
DT   10-MAY-2005 (TrEMBLrel. 30, Created)
DT   10-MAY-2005 (TrEMBLrel. 30, Last sequence update)
DT   10-MAY-2005 (TrEMBLrel. 30, Last annotation update)
DE   Hypothetical LOC496985.
GN   Name=LOC496985;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; 
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; 
OC   Xenopodinae; Xenopus; Silurana. 
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole body;
RX   MEDLINE=22388257; PubMed=12477932 [NCBI, ExPASy, EBI, Israel, Japan]; DOI=10.1073/pnas.242603899;
RA   Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G.,
RA   Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D.,
RA   Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K.,
RA   Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F.,
RA   Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L.,
RA   Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E.,
RA   Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C.,
RA   Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J.,
RA   Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H.,
RA   Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W.,
RA   Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A.,
RA   Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A.,
RA   Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G.,
RA   Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C.,
RA   Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M.,
RA   Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E.,
RA   Schnerch A., Schein J.E., Jones S.J.M., Marra M.A.;
RT   "Generation and initial analysis of more than 15,000 full-length human
RT   and mouse cDNA sequences.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole body;
RA   Klein S., Gerhard D.S.;
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
DR   EMBL; BC088873; AAH88873.1; -; mRNA. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   GO; GO:0016021; C:integral to membrane; IEA.
DR   GO; GO:0016020; C:membrane; IEA.
DR   GO; GO:0005267; F:potassium channel activity; IEA.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA.
DR   GO; GO:0006811; P:ion transport; IEA.
DR   GO; GO:0006813; P:potassium ion transport; IEA.
DR   InterPro; IPR003280; K+channel_2pore.
DR   InterPro; IPR001622; K+channel_pore.
DR   InterPro; IPR001779; TWIK1_channel.
DR   InterPro; IPR005409; TWIK2_channel.
DR   InterPro; IPR005408; TWIK_channel.
DR   InterPro; Graphical view of domain structure.
DR   PRINTS; PR01333; 2POREKCHANEL.
DR   PRINTS; PR01096; TWIK1CHANNEL.
DR   PRINTS; PR01587; TWIK2CHANNEL.
DR   PRINTS; PR01586; TWIKCHANNEL.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain]
DR   HOVERGEN [Family / Alignment / Tree]
DR   ProtoMap; Q5HZV4.
DR   PRESAGE; Q5HZV4.
DR   ModBase; Q5HZV4.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   Hypothetical protein; Ion transport; Ionic channel; Transmembrane;
KW   Transport.
SQ   SEQUENCE   330 AA;  37602 MW;  6C7570942E084B21 CRC64;
     MLQALATNPC LRLIQRNQTC WCFVLLMLGY LLFLLIGAAI FSAVELPHEH VLREELLDLK
     HRYLQENECL SEERLESFLS RVLEASNYGV SMLNNVSGNP NWDFTSALFF VSTVLSTTGY
     GHTVPLSNAG KTFCIIYSII GIPLTLLLFT ALVQRIMVHV THRPISYFHL RWGYNKQTVA
     VVHALVIGFV AILCFFLIPA AIFSALEDDW NFLESFYFCF ISLSTIGLGD YVPAEGQNQR
     YRQLYKFGIT CYLILGLIVM LVVLETFCEL QGLKKFRKMF YRKKMKEGDQ LNIIEHDQLT
     LASISEQAAS LKEEQMLDEH SVPDGPLNSD
//