Swiss-Prot entry

ID   KCNE3_RAT      STANDARD;      PRT;   107 AA.
AC   Q9JJV7;
DT   16-OCT-2001 (Rel. 40, Created)
DT   16-OCT-2001 (Rel. 40, Last sequence update)
DT   10-MAY-2005 (Rel. 47, Last annotation update)
DE   Potassium voltage-gated channel subfamily E member 3 (Minimum
DE   potassium ion channel-related peptide 2) (Potassium channel beta
DE   subunit MiRP2) (MinK-related peptide 2).
GN   Name=Kcne3;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; 
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; 
OC   Muridae; Murinae; Rattus. 
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Wistar; TISSUE=Colon;
RX   MEDLINE=21114838; PubMed=11220365 [NCBI, ExPASy, EBI, Israel, Japan]; DOI=10.1007/s002320010045;
RA   Kunzelmann K., Huebner M., Schreiber R., Levy-Holzman R., Garty H.,
RA   Bleich M., Warth R., Slavik M., von Hahn T., Greger R.;
RT   "Cloning and function of the rat colonic epithelial K+ channel
RT   KVLQT1.";
RL   J. Membr. Biol. 179:155-164(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ancillary protein that assembles as a beta subunit with
CC       a voltage-gated potassium channel complex of pore-forming alpha
CC       subunits. Modulates the gating kinetics and enhances stability of
CC       the channel complex. Associated with KCNC4/Kv3.4 is proposed to
CC       form the subthreshold voltage-gated potassium channel in skeletal
CC       muscle and to establish the resting membrane potential (RMP) in
CC       muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal
CC       cAMP-stimulated potassium channel involved in chloride secretion
CC       (By similarity).
CC   -!- SUBUNIT: Associates with KCNC4/Kv3.4. May associate with
CC       KCNQ1/KVLQT1 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Type I membrane protein.
CC   -!- SIMILARITY: Belongs to the potassium channel KCNE family.
CC   --------------------------------------------------------------------------
CC   This Swiss-Prot entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use as long as its content is in no way modified and this statement is not
CC   removed.
CC   --------------------------------------------------------------------------
DR   EMBL; AJ271742; CAB72139.1; -; mRNA. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   EMBL; BC086406; AAH86406.1; -; mRNA. [EMBL / GenBank / DDBJ] [CoDingSequence]
DR   Ensembl; ENSRNOG00000017054; Rattus_norvegicus
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS.
DR   InterPro; IPR000369; ISK_Channel.
DR   InterPro; IPR005426; KCNE_beta3.
DR   InterPro; Graphical view of domain structure.
DR   PRINTS; PR01606; KCNE3CHANNEL.
DR   PRINTS; PR00168; KCNECHANNEL.
DR   CMR; Q9JJV7.
DR   ProDom [Domain structure / List of seq. sharing at least 1 domain]
DR   HOVERGEN [Family / Alignment / Tree]
DR   BLOCKS; Q9JJV7.
DR   ProtoNet; Q9JJV7.
DR   ProtoMap; Q9JJV7.
DR   PRESAGE; Q9JJV7.
DR   DIP; Q9JJV7.
DR   ModBase; Q9JJV7.
DR   SWISS-2DPAGE; GET REGION ON 2D PAGE.
KW   Glycoprotein; Ion transport; Ionic channel; Potassium;
KW   Potassium channel; Potassium transport; Transmembrane; Transport;
KW   Voltage-gated channel.
FT   TRANSMEM     62     82       Potential.
FT   TOPO_DOM     83    107       Cytoplasmic (Potential).
FT   CARBOHYD      5      5       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD     22     22       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD     45     45       N-linked (GlcNAc...) (Potential).
SQ   SEQUENCE   107 AA;  12001 MW;  D0F62FE342E66E8F CRC64;
     METSNGTETW YKSLHAVLKA LNTTLHSHLL CRPGPGPGSG TGPDNQTEDH RASLPGRNDN
     SYMYILFVMF LFAVTVGSLI LGYTRSRKVD KRSDPYHVYI KNRVSMI
//