KChannelDB Groups of residues showing correlated mutational behaviour
2005, KChannelDB.
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*** Files used in the CMA analysis ***
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1 : Q99PR2_CAVPO 433 Q99PR2 Inward rectifier potassium cha
2 : Q8NG63_HUMAN 433 Q8NG63 KCNJ12 -- Inward rectifier potassium cha
3 : Q9ESD9_CAVPO 433 Q9ESD9 KCNJ12 -- Inwardly-rectifying potassium
4 : Q8CCR0_MOUSE 427 Q8CCR0 Kcnj12 -- Mus musculus adult male olfact
5 : Q6U7S0_RAT 427 Q6U7S0 Inward rectifier potassium cha
6 : Q5SU77_MOUSE 529 Q5SU77 Kcnj12 -- Potassium inwardly-rectifying
7 : Q9D3L6_MOUSE 427 Q9D3L6 Kcnj12 -- Mus musculus 6 days neonate he
8 : IRK12_HUMAN 432 Q14500 KCNJ12 -- ATP-sensitive inward rectifier
9 : IRK12_RAT 427 P52188 Kcnj12 -- ATP-sensitive inward rectifier
10 : IRK2_RABIT 427 P49656 KCNJ2 -- Inward rectifier potassium cha
11 : IRK2_CANFA 427 Q9MYY9 KCNJ2 -- Inward rectifier potassium cha
12 : IRK12_MOUSE 427 P52187 Kcnj12 -- ATP-sensitive inward rectifier
13 : IRK2_CAVPO 427 P52185 KCNJ2 -- Inward rectifier potassium cha
14 : IRK2_BOVIN 427 O19182 KCNJ2 -- Inward rectifier potassium cha
15 : Q6L5N3_HUMAN 433 Q6L5N3 kcnj12x-- Hkir2.2x.
16 : IRK2_RAT 427 Q64273 Kcnj2 -- Inward rectifier potassium cha
17 : IRK2_PIG 427 O18839 KCNJ2 -- Inward rectifier potassium cha
18 : IRK2_HUMAN 427 P63252 KCNJ2 -- Inward rectifier potassium cha
19 : IRK2_MACMU 427 P63253 KCNJ2 -- Inward rectifier potassium cha
20 : IRK2_MOUSE 428 P35561 Kcnj2 -- Inward rectifier potassium cha
21 : O42229_CHICK 427 O42229 IRK1 -- Inward rectifier potassium cha
22 : Q9PUE1_COLLI 427 Q9PUE1 Inward rectifier channel Kir 2
23 : IRK2_CHICK 427 P52186 KCNJ2 -- Inward rectifier potassium cha
24 : IRKI_HUMAN 432 Q15756 KCNJN1 -- Inward rectifying K(+) channel
25 : IRK4_HUMAN 445 P48050 KCNJ4 -- Inward rectifier potassium cha
26 : IRK4_MESAU 444 Q64198 KCNJ4 -- Inward rectifier potassium cha
27 : IRK4_RAT 446 P52190 Kcnj4 -- Inward rectifier potassium cha
28 : IRK4_MOUSE 445 P52189 Kcnj4 -- Inward rectifier potassium cha
29 : Q9ESD8_CAVPO 443 Q9ESD8 KCNJ4 -- Inwardly-rectifying potassium
30 : IRK6_HUMAN 423 P48051 KCNJ6 -- G protein-activated inward rec
31 : Q8C4T8_MOUSE 414 Q8C4T8 Kcnj6 -- Mus musculus 10 days neonate c
32 : Q8QZW1_RAT 414 Q8QZW1 GIRK2-2-- GIRK2.
33 : Q5NVJ6_PONPY 423 Q5NVJ6 DKFZp45--0Hypothetical protein DKFZp459A
34 : IRK6_MESAU 425 P49658 KCNJ6 -- G protein-activated inward rec
35 : IRK6_RAT 425 P48550 Kcnj6 -- G protein-activated inward rec
36 : IRK6_MOUSE 425 Q9QYH5 Kcnj6 -- G protein-activated inward rec
37 : IRK9_HUMAN 393 Q92806 KCNJ9 -- G protein-activated inward rec
38 : IRK9_RAT 393 Q63511 Kcnj9 -- G protein-activated inward rec
39 : IRK9_MOUSE 393 P48543 Kcnj9 -- G protein-activated inward rec
40 : Q5JW75_HUMAN 393 Q5JW75 KCNJ9 -- Potassium inwardly-rectifying
41 : IRK5_HUMAN 419 P48544 KCNJ5 -- G protein-activated inward rec
42 : IRK5_RAT 419 P48548 Kcnj5 -- G protein-activated inward rec
43 : IRK5_PIG 419 O02670 KCNJ5 -- G protein-activated inward rec
44 : IRK8_HUMAN 424 Q15842 KCNJ8 -- ATP-sensitive inward rectifier
45 : Q99N30_CAVPO 424 Q99N30 Inward rectifier potassium cha
46 : Q8WMQ7_RABIT 424 Q8WMQ7 KIR6.1 -- Inward rectifier potassium cha
47 : IRK8_MOUSE 424 P97794 Kcnj8 -- ATP-sensitive inward rectifier
48 : IRK5_MOUSE 419 P48545 Kcnj5 -- G protein-activated inward rec
49 : IRK8_RAT 424 Q63664 Kcnj8 -- ATP-sensitive inward rectifier
50 : Q6AYX1_RAT 424 Q6AYX1 Kcnj8 -- Potassium inwardly-rectifying
51 : IRK11_RABIT 390 O02822 KCNJ11 -- ATP-sensitive inward rectifier
52 : IRK11_RAT 390 P70673 Kcnj11 -- ATP-sensitive inward rectifier
53 : Q8AXC9_RANCA 390 Q8AXC9 ATP sensitive potassium channe
54 : IRK11_MOUSE 390 Q61743 Kcnj11 -- ATP-sensitive inward rectifier
55 : Q7LZ07_RANCA 390 Q7LZ07 Inwardly-rectifying ATP-sensit
56 : IRK11_CAVPO 390 Q9JHJ9 KCNJ11 -- ATP-sensitive inward rectifier
57 : IRK11_HUMAN 390 Q14654 KCNJ11 -- ATP-sensitive inward rectifier
58 : Q91658_XENLA 429 Q91658 xir -- XIR.
59 : Q788V5_XENLA 404 Q788V5 xir -- XIR.
60 : Q95J93_RABIT 424 Q95J93 ATP-sensitive inward rectifier
61 : IRK14_RAT 434 O70596 Kcnj14 -- ATP-sensitive inward rectifier
62 : IRK14_MOUSE 434 Q8JZN3 Kcnj14 -- ATP-sensitive inward rectifier
63 : Q866Z9_RABIT 390 Q866Z9 Kir 6.2 ATP-sensitive inward r
64 : Q9EP58_CAVPO 439 Q9EP58 KCNJ14 -- Inwardly-rectifying potassium
65 : IRK14_HUMAN 436 Q9UNX9 KCNJ14 -- ATP-sensitive inward rectifier
66 : Q9ESX9_CAVPO 501 Q9ESX9 girk1 -- Inward rectifying potassium ch
67 : IRK3_RAT 501 P63251 Kcnj3 -- G protein-activated inward rec
68 : IRK3_MOUSE 501 P63250 Kcnj3 -- G protein-activated inward rec
69 : IRK3_HUMAN 501 P48549 KCNJ3 -- G protein-activated inward rec
70 : Q8TBI0_HUMAN 501 Q8TBI0 KCNJ3 -- Potassium inwardly-rectifying
71 : IRK3_CHICK 492 Q90854 KCNJ3 -- G protein-activated inward rec
72 : Q5RH88_BRARE 416 Q5RH88 OTTDARP--0Novel protein similar to verte
73 : IRK1_HUMAN 391 P48048 KCNJ1 -- ATP-sensitive inward rectifier
74 : IRK1_MOUSE 372 O88335 Kcnj1 -- ATP-sensitive inward rectifier
75 : IRK1_RAT 391 P35560 Kcnj1 -- ATP-sensitive inward rectifier
76 : Q5R883_PONPY 372 Q5R883 DKFZp46--0Hypothetical protein DKFZp469K
77 : Q6AX29_XENLA 372 Q6AX29 MGC8633-- MGC86330 protein.
78 : Q8BH37_MOUSE 419 Q8BH37 Kcnj16 -- Mus musculus adult male olfact
79 : Q5R205_BRARE 432 Q5R205 zKir6.2-- Kir6.2 protein.
80 : Q8CIB3_MOUSE 419 Q8CIB3 Kcnj16 -- Potassium inwardly-rectifying
81 : Q68G21_RAT 419 Q68G21 Kcnj16 -- Potassium inwardly-rectifying
82 : IRK16_RAT 419 P52191 Kcnj16 -- Inward rectifier potassium cha
83 : Q8R440_CAVPO 419 Q8R440 KCNJ16 -- Inwardly-rectifying potassium
84 : IRK16_MOUSE 419 Q9Z307 Kcnj16 -- Inward rectifier potassium cha
85 : Q8N538_HUMAN 418 Q8N538 KCNJ16 -- Potassium inwardly-rectifying
86 : Q9VCQ0_DROME 532 Q9VCQ0 Ir -- CG6747-PA (Inwardly rectifying
87 : IRK16_HUMAN 418 Q9NPI9 KCNJ16 -- Inward rectifier potassium cha
88 : Q95UP7_DROME 422 Q95UP7 Ir -- Potassium inwardly rectifying
89 : Q5RAA3_PONPY 418 Q5RAA3 DKFZp46--0Hypothetical protein DKFZp469L
90 : IRK10_MOUSE 379 Q9JM63 Kcnj10 -- ATP-sensitive inward rectifier
91 : IRK10_RAT 379 P49655 Kcnj10 -- ATP-sensitive inward rectifier
92 : IRK10_HUMAN 379 P78508 KCNJ10 -- ATP-sensitive inward rectifier
93 : Q8C7Z5_MOUSE 379 Q8C7Z5 Kcnj10 -- Mus musculus 0 day neonate cer
94 : Q8WST7_HALRO 745 Q8WST7 TuIRK -- Inwardly rectifying potassium
95 : IRK15_HUMAN 375 Q99712 KCNJ15 -- ATP-sensitive inward rectifier
96 : IRK15_RAT 405 Q91ZF1 Kcnj15 -- ATP-sensitive inward rectifier
97 : Q5RDF7_PONPY 375 Q5RDF7 DKFZp46--1Hypothetical protein DKFZp469F
98 : Q5R827_PONPY 375 Q5R827 DKFZp46--0Hypothetical protein DKFZp469L
99 : IRK15_MOUSE 375 O88932 Kcnj15 -- ATP-sensitive inward rectifier
100 : IRK15_CAVPO 375 O70339 KCNJ15 -- ATP-sensitive inward rectifier
101 : Q63ZM2_XENLA 378 Q63ZM2 LOC4947-- LOC494778 protein.
102 : Q21458_CAEEL 514 Q21458 irk-2 -- Inward rectifying k (Potassium
103 : Q5WN69_CAEBR 521 Q5WN69 CBG0812-- Hypothetical protein CBG08126.
104 : Q9VCL9_DROME 453 Q9VCL9 Irk2 -- CG4370-PA, isoform A (GH11459p
105 : Q61H54_CAEBR 503 Q61H54 CBG1088-- Hypothetical protein CBG10884.
106 : IRK1_CAEEL 505 P52192 irk-1 -- Inward rectifier potassium cha
107 : Q98975_ONCMA 423 Q98975 sWIRK -- Weakly inward rectifying potas
108 : Q8R5M1_RAT 327 Q8R5M1 GIRK2B--- GIRK2B (G protein coupled inwa
109 : Q7Z2B6_CLOSI 333 Q7Z2B6 ATP-sensitive potassium channe
110 : Q8C8Y6_MOUSE 309 Q8C8Y6 Kcnj6 -- Mus musculus adult retina cDNA
111 : Q6PCJ5_XENLA 369 Q6PCJ5 Kcnj1 -- Kcnj1 protein.
112 : Q7SY43_BRARE 370 Q7SY43 ORFName--zPotassium inwardly-rectifying
113 : IRK13_RAT 360 O70617 Kcnj13 -- Inward rectifier potassium cha
114 : IRK13_CAVPO 360 Q9QZ65 KCNJ13 -- Inward rectifier potassium cha
115 : IRK13_HUMAN 360 O60928 KCNJ13 -- Inward rectifier potassium cha
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*** Summarized correlation networks ***
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1 ( 0) LLLLLLLLLTTLTTLTTTTTTTTL.....IIIIIII....AAAPPPPAPPEEEEEEEAAPEEEAGSSSSSVPE.E..NGNNNNNN.N.NKKKKYHHHHHHKLLPLLTI.IH....
2 ( 0) VVVVVVVVVMMVMLVMLMMMMMMV.....HHHHHHHMMMMRRREEEEREEYYYYYYYRREAAYAPGGGGGVES.R..VFVVVVVAMAMVVVVVIIIIILMVVVFAADH.HS....
3 ( 0) TTTTTTTTTAATAATAAAAAAAAT.....QQQQQQQAAAADDDEEEEDEEVVVVVVVEEEGGVGGLLLLLSEMMMMMDLDDDDDDYDYDYYYYNGGGGGSYKKPFFVQ.QD....
4 ( 0) MMMMMMMMMVVMVVMVVVVVVVVM.....PPPPPPPQQQQYYYYYYYYYYLLLLLLLDDYAALPLQQQQQTFFFFLFSLSSSPSAIAIPYYYYDMMMMMVYNNRTTLP.PLM...
5 ( 0) SSSSSSSSSAASAASAAAAAAAASMMMMMKKKKKKKEEEEVIIVVVVIVVTTTTTTTPPVGGTGCPPPPPSAKKKKSKTKKKKKKLKLKSSSSMSSSSSTSKKQAAKK.KSTMMM
6 ( 0) GGGGGGGGGNNGNNGNNNNNNNNGHHHHHLLLLLLLNNNNPPPLLLLPLLRRRRRRRKKLLLRLRQQQQQALHHHHYYRYYYYYYLYLYQQQQHSSSSSRQKKPRRPL.LSRDED
7 ( 0) AAAAAAAAAGGAGGAGGGGGGGGAGGGGGPPPPPPPAAAAIIIAAAAIAALLLLLLLRRACCLCNGGGGGSPLLLLFPLPPPPPPFPFPTTTTATATTAPTYYSRRLP.PCSSSS
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74 ( 149) SSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTTTTTTTTTTTTTSSSSTSSSSSSSSSTTSSSSSSAAAAAASSSSSSSSSSSSSSSSSSTTTTSTTTTTTTSSSSSTTSTTSHHH
212 ( 0) QQQQQQQQQQQQQQQQQQQQQQQQQQQQQKKKKKKKKKKKKKKQQQQKQQQQQQQQQKKQQQQQQKKKKKKQKKKKKQQQQQQQQQQQQKKKKQKKKKKKKQQQQQKKQKKKVVV
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76 ( 151) LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLFFFFFLMLLLLLLALAMFFFFLFFFFFFFSSLSSFLLLCFLLL
111 ( 0) FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFLMMLMFFFFFFFFMFMFLLLLFLLLLLLLEEFVVLFLFFMFFF
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82 ( 157) FFFFFFSFFFFFFFFFFFFFFFFFFFFFFWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWFFWFFWWWWWWWWWWWWFWFFFFFFWFWFWWWWYYYYYYYWYYWYYWWWWYWWWW
140 ( 0) VVVVVVVVVVVVVVVVVVVVVVVVVVVVVIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIVVIVVIIIIIIIIIIIIVIVVVVVVIVIVIIIIIIIIIIIIIIIGGIIIIIVIII
249 ( 0) IIIIIIIIIIIIIIIIIIIIIIIIIIIIILLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIILIILLLLLLLLLLLLVLVVVVVITVTVLLLLQMMMMMMLIIMTTLLLLLLLLL
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89 ( 0) HHHHHHHHHHHHHHHHHHHHHHHHHHHHHRRRRRRRRRRRRRRHHHHRHHHHHHHHHRRHHHHHHRRRRRRHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHRHRHNNNN
122 ( 0) QQQQQQQQQQQQQQQQQQQQQQQQQQQQQEEEEEEEEEEEEEEQQQQEQQQQQQQQQEEQQQQQQEEEEEEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHHQEQEQQQQQ
135 ( 0) EEEEEEEEEEEEEEEEEEEEEEEEEEEEEKKKKKKKQQQQKKKEEEEKEEEEEEEEEKKEEEEEEKKKKKKRQQQQQEEEEEEEEEEEEEEEEEEEEEEEEAAEEEEKEKEQDDD
139 ( 0) AAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGAAAAGAAAAAAAAAGGAAAAAAGGGGGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTAAAAGAGAGAAA
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121 ( 0) TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTVVVVTVVVVVVVVVTTVTTVTTTTTTTTVTTTTTTVTTTTTTTTTTSSSSTSSSSSSSTTTTTSTVTSTTTT
187 ( 0) DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDNNNNDNNQHQHQHHDDNDDQDDDDDDDDNGGGGGDNDDDDDDDDDDNNNNDNNNNNNEDDDDDEDQDNKDDD
203 ( 0) HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHMMMMHMMMMMMMMMHHMHHMHHHHHHHHMLLLLLHMHHHHHHHHHHLLLLHLLLLLLLSSHHHLHMHLLPPP
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166 ( 0) AAAAAAAAGAAAAAAAAAAAAAAVAAPAASSSSSSSSSSSSSSAAAASAAAAAAASASSAAAAAASSSSSSASSSSSAAAAAAAASASAAAAASAAAAAAAAATAAASASASAAA
261 ( 0) LLLLLLLLLLLLLLLLLLLLLLLLLLLLLFFFFFFFFFFFFFFLLLLFLLLLLLLLLFFLLLLLLFFFFFFLFFFFFLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLFLFLFLLL
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169 ( 0) KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKNNNNKKKHHHHKHHHHHHHHHKKHKKHKKKKKKKKHKKKKKRNRRRRRRKRKRKKKKKKKKKKKKIIKKKKKHKKKKKK
277 ( 0) VVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVVIIIIVIIIIIIIIIVVIVVIVVVVVVVVIVVVVVLILLLLLLVLVLVVVVIVVVVVVVIIVIILVIVVVVVV
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175 ( 0) LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIIIIIILIIIIIILILIIIIILIIIIIIILLLIIVLLLIIIII
207 ( 0) AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASSSSSGAGGGGGGAGAGCCCCACCCCCCCAAAAACAAACSVVV
226 ( 0) PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPIIIIIMPMMMMMMPMPMRRRRPLLLLLLHPPTPPRPPPLIEQK
281 ( 0) EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDDDIEIIIIIIEIEISSSSENNNNNNSEEEEESEEENDSSS
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210 ( 0) RRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRHHHHHHHRRRRRHRRRRRRRRRYYYYYRQRRRRRRRRRRTTTTRSSSSSSTRRRRRTRHRYYSSS
234 ( 0) VVVVVVVVVVVVVVVVVVVVVVVVVVVVLVVVVVVVVVVVVVVVVVVVVVMMMMMMMVVVVVHVVVVVVVVTFFFFFVVVVVVVVIVIVFFFFLFFFFFFFVVIVVFVMVFFFFF
