KChannelDB: Point mutations extracted from the literature - KCNK5_HUMAN

2005, KChannelDB.

This data was extracted from medline abstracts and full text papers (when available) in an automated manner.

Each point mutation is linked to the entry specific to the residue position. Citations are linked to the list of point mutations found in the corresponding articles. The last column allows you to go back to the original text via Medline.

Protein	KCNK5_HUMAN (KCNK5,TASK)	Swiss-Prot Cross-reference table Family page
Family alignments	Two-pore channels (K2p) Potassium channels 4 TMs 2P

Mutation Location General numbering Reference
G102A Loop 1-2 Morton MJ et al., Am J Physiol Renal Physiol 2005 Medline

G207A Loop 3-4 Morton MJ et al., Am J Physiol Renal Physiol 2005 Medline

E228Q TRANSMEM IV 444 Morton MJ et al., Am J Physiol Renal Physiol 2005 Medline

E251Q C-term Morton MJ et al., Am J Physiol Renal Physiol 2005 Medline

Mutation	Location	General numbering	Reference
G102A	Loop 1-2		Morton MJ et al., Am J Physiol Renal Physiol 2005	Medline
G207A	Loop 3-4		Morton MJ et al., Am J Physiol Renal Physiol 2005	Medline
E228Q	TRANSMEM IV	444	Morton MJ et al., Am J Physiol Renal Physiol 2005	Medline
E251Q	C-term		Morton MJ et al., Am J Physiol Renal Physiol 2005	Medline

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005