KChannelDB: Point mutations extracted from the literature - KCNH1_BOVIN

2005, KChannelDB.

This data was extracted from medline abstracts and full text papers (when available) in an automated manner.

Each point mutation is linked to the entry specific to the residue position. Citations are linked to the list of point mutations found in the corresponding articles. The last column allows you to go back to the original text via Medline.

Protein	KCNH1_BOVIN (KCNH1,EA)	Swiss-Prot Cross-reference table Family page
Protein isoforms	2
Family alignments	eag related KCNH (Kv10-12) K+ voltage-gated channels (Kv1-12,Kca2-5) Potassium channels 6 TMs

Mutation Location General numbering Reference
T16C N-term Becchetti A et al., Pflugers Arch 2000 Medline

I319C Loop 3-4 Schonherr R et al., Neuron 2002 Medline

S321C Loop 3-4 Schonherr R et al., Neuron 2002 Medline

L322C Loop 3-4 Schonherr R et al., Neuron 2002 Medline

K327C Loop 3-4 Schonherr R et al., Neuron 2002 Medline

T432S Loop 5-6 Chen J et al., Proc Natl Acad Sci U S A 2002 Medline

A443S Loop 5-6 Chen J et al., Proc Natl Acad Sci U S A 2002 Medline

Mutation	Location	Reference
T16C	N-term	Becchetti A et al., Pflugers Arch 2000	Medline
I319C	Loop 3-4	Schonherr R et al., Neuron 2002	Medline
S321C	Loop 3-4	Schonherr R et al., Neuron 2002	Medline
L322C	Loop 3-4	Schonherr R et al., Neuron 2002	Medline
K327C	Loop 3-4	Schonherr R et al., Neuron 2002	Medline
T432S	Loop 5-6	Chen J et al., Proc Natl Acad Sci U S A 2002	Medline
A443S	Loop 5-6	Chen J et al., Proc Natl Acad Sci U S A 2002	Medline

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005