KChannelDB: Point mutations extracted from the literature - KCNA4_MUSPF

2005, KChannelDB.

This data was extracted from medline abstracts and full text papers (when available) in an automated manner.

Each point mutation is linked to the entry specific to the residue position. Citations are linked to the list of point mutations found in the corresponding articles. The last column allows you to go back to the original text via Medline.

Protein	KCNA4_MUSPF (KCNA)	Swiss-Prot Cross-reference table Family page
Family alignments	shaker related KCNA (Kv1) K+ voltage-gated channels (Kv1-12,Kca2-5) Potassium channels 6 TMs

Mutation Location General numbering Reference
H508F Loop 5-6 Claydon TW et al., J Physiol 2000 Medline

H508Q Loop 5-6 Claydon TW et al., J Physiol 2000 Medline

K532Q Loop 5-6 Claydon TW et al., J Physiol 2000 Medline

K532Y Loop 5-6 Claydon TW et al., J Physiol 2000 Medline

K532Y Loop 5-6 Li X et al., Am J Physiol Heart Circ Physiol 2003 Medline

Mutation	Location	Reference
H508F	Loop 5-6	Claydon TW et al., J Physiol 2000	Medline
H508Q	Loop 5-6	Claydon TW et al., J Physiol 2000	Medline
K532Q	Loop 5-6	Claydon TW et al., J Physiol 2000	Medline
K532Y	Loop 5-6	Claydon TW et al., J Physiol 2000	Medline
K532Y	Loop 5-6	Li X et al., Am J Physiol Heart Circ Physiol 2003	Medline

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005