KChannelDB: Point mutations extracted from the literature - IRK11_MOUSE

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This data was extracted from medline abstracts and full text papers (when available) in an automated manner.

Each point mutation is linked to the entry specific to the residue position. Citations are linked to the list of point mutations found in the corresponding articles. The last column allows you to go back to the original text via Medline.

ProteinIRK11_MOUSE (Kcnj1)Swiss-Prot
Cross-reference table
Family page
Family alignments Inward rectifiers (Kir)
Potassium channels 2 TMs

MutationLocationGeneral numberingReference
Y12XN-term Huopio H et al., Am J Physiol Endocrinol Metab 2002Medline
R34CN-term Ribalet B et al., Biophys J 2003Medline
F35VN-term Sagen JV et al., Diabetes 2004Medline
K38CN-term Ribalet B et al., Biophys J 2003Medline
C42AN-term Proks P et al., Br J Pharmacol 2001Medline
H46AN-term Xu H et al., J Biol Chem 2001Medline
R50CN-term Ribalet B et al., Biophys J 2003Medline
R50EN-term Ribalet B et al., Biophys J 2003Medline
R50GN-term Ribalet B et al., Biophys J 2003Medline
R50GN-term Seino S et al., Prog Biophys Mol Biol 2003Medline
R50KN-term Ribalet B et al., Biophys J 2003Medline
V59MN-term Sagen JV et al., Diabetes 2004Medline
K67MN-term Proks P et al., Br J Pharmacol 2001Medline
K67QN-term Proks P et al., Br J Pharmacol 2001Medline
H70AN-term Xu H et al., J Biol Chem 2001Medline
W83FTRANSMEM I150Proks P et al., J Gen Physiol 2001Medline
W91RTRANSMEM I158Huopio H et al., Am J Physiol Endocrinol Metab 2002Medline
E126DLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
E126QLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
V127ALoop 1-2 Proks P et al., J Gen Physiol 2001Medline
V127DLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
V127KLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
V127SLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
V127TLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
G132ALoop 1-2 Seino S et al., Prog Biophys Mol Biol 2003Medline
F133ALoop 1-2 Seino S et al., Prog Biophys Mol Biol 2003Medline
F133VLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
F133YLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
G134ALoop 1-2 Seino S et al., Prog Biophys Mol Biol 2003Medline
G135FLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
M137CLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
T139VLoop 1-2 Proks P et al., J Gen Physiol 2001Medline
L147PTRANSMEM II245Huopio H et al., Am J Physiol Endocrinol Metab 2002Medline
N160DTRANSMEM II258Markworth E et al., Diabetes 2000Medline
L164CTRANSMEM II262Proks P et al., J Gen Physiol 2001Medline
C166STRANSMEM II264Proks P et al., Br J Pharmacol 2001Medline
C166STRANSMEM II264Xu H et al., J Biol Chem 2001Medline
C166STRANSMEM II264Proks P et al., J Gen Physiol 2001Medline
T171KC-term Xu H et al., J Biol Chem 2001Medline
Q173AC-term Li L et al., Biophys J 2000Medline
H175AC-term Xu H et al., J Biol Chem 2001Medline
H175AC-term Wu J et al., J Physiol 2002Medline
H175CC-term Xu H et al., J Biol Chem 2001Medline
H175DC-term Xu H et al., J Biol Chem 2001Medline
H175EC-term Xu H et al., J Biol Chem 2001Medline
H175KC-term Xu H et al., J Biol Chem 2001Medline
H175KC-term Wu J et al., J Physiol 2002Medline
H175NC-term Xu H et al., J Biol Chem 2001Medline
H175QC-term Xu H et al., J Biol Chem 2001Medline
H175RC-term Xu H et al., J Biol Chem 2001Medline
R176AC-term Li L et al., Biophys J 2000Medline
R176AC-term Ribalet B et al., Biophys J 2003Medline
R176CC-term Ribalet B et al., Biophys J 2003Medline
R177AC-term Li L et al., Biophys J 2000Medline
R177AC-term Ribalet B et al., Biophys J 2003Medline
R177CC-term Ribalet B et al., Biophys J 2003Medline
E179QC-term Li L et al., Biophys J 2000Medline
E179QC-term Kubo Y et al., J Physiol 2001Medline
E179QC-term Xu H et al., J Biol Chem 2001Medline
T180AC-term Light PE et al., FASEB J 2001Medline
I182AC-term Li L et al., Biophys J 2000Medline
I182KC-term Li L et al., Biophys J 2000Medline
I182LC-term Li L et al., Biophys J 2000Medline
I182QC-term Li L et al., Biophys J 2000Medline
I182RC-term Li L et al., Biophys J 2000Medline
I182WC-term Li L et al., Biophys J 2000Medline
I182XC-term Li L et al., Biophys J 2000Medline
K185EC-term Wu J et al., J Physiol 2002Medline
K185EC-term Proks P et al., Br J Pharmacol 2001Medline
K185EC-term Wu J et al., J Membr Biol 2002Medline
K185QC-term Li L et al., Biophys J 2000Medline
K185QC-term Dabrowski M et al., J Physiol 2003Medline
K185QC-term Koster JC et al., Circ Res 2001Medline
K185QC-term Ribalet B et al., Biophys J 2003Medline
K185QC-term Rajashree R et al., Am J Physiol Heart Circ Physiol 2002Medline
K185QC-term Seino S et al., Prog Biophys Mol Biol 2003Medline
K185QC-term Proks P et al., Br J Pharmacol 2001Medline
H186AC-term Xu H et al., J Biol Chem 2001Medline
R192AC-term Lin YW et al., J Gen Physiol 2003Medline
R192AC-term Ribalet B et al., Biophys J 2003Medline
R192CC-term Ribalet B et al., Biophys J 2003Medline
R192EC-term Lin YW et al., J Gen Physiol 2003Medline
H193NC-term Xu H et al., J Biol Chem 2001Medline
H193QC-term Xu H et al., J Biol Chem 2001Medline
R201AC-term Ribalet B et al., Biophys J 2003Medline
R201CC-term Ribalet B et al., Biophys J 2003Medline
R201HC-term Sagen JV et al., Diabetes 2004Medline
R206AC-term Ribalet B et al., Biophys J 2003Medline
R206CC-term Ribalet B et al., Biophys J 2003Medline
K207NC-term Proks P et al., Br J Pharmacol 2001Medline
H216QC-term Xu H et al., J Biol Chem 2001Medline
K222AC-term Ribalet B et al., Biophys J 2003Medline
T224AC-term Lin YF et al., EMBO J 2000Medline
T224DC-term Lin YF et al., EMBO J 2000Medline
E229AC-term Lin YW et al., J Gen Physiol 2003Medline
E229CC-term Lin YW et al., J Gen Physiol 2003Medline
E229RC-term Lin YW et al., J Gen Physiol 2003Medline
H234AC-term Xu H et al., J Biol Chem 2001Medline
H259AC-term Xu H et al., J Biol Chem 2001Medline
H276AC-term Xu H et al., J Biol Chem 2001Medline
H277QC-term Xu H et al., J Biol Chem 2001Medline
R301AC-term Lin YW et al., J Gen Physiol 2003Medline
R301AC-term Ribalet B et al., Biophys J 2003Medline
R301CC-term Ribalet B et al., Biophys J 2003Medline
R301EC-term Lin YW et al., J Gen Physiol 2003Medline
R314AC-term Lin YW et al., J Gen Physiol 2003Medline
R314AC-term Ribalet B et al., Biophys J 2003Medline
R314CC-term Lin YW et al., J Gen Physiol 2003Medline
R314CC-term Ribalet B et al., Biophys J 2003Medline
R314EC-term Lin YW et al., J Gen Physiol 2003Medline
Y330CC-term Sagen JV et al., Diabetes 2004Medline
K332NC-term Proks P et al., Br J Pharmacol 2001Medline
F333IC-term Sagen JV et al., Diabetes 2004Medline
G334DC-term Li L et al., Biophys J 2000Medline
G334DC-term Markworth E et al., Diabetes 2000Medline
S372AC-term Lin YF et al., EMBO J 2000Medline
S372DC-term Lin YF et al., EMBO J 2000Medline

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F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005