KChannelDB: Extraction of mutation data from the literature

2005, KChannelDB.

This data was extracted from Medline abstracts and full texts (when available) in an automated manner.

The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation T65P was found are listed after the table.

The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.

Point mutation T65P in KCAB1_HUMAN

Point mutation:	T65P
Domain:	Not determined
General numbering (KChannelDB):	-
Protein:	KCAB1_HUMAN (KCNAB1,KCNA1)	Swiss-Prot Cross-reference table Family page
Protein isoforms	3
Other point mutations / same protein	List of mutations in KCAB1_HUMAN
Family alignments	Potassium channel beta subunits KvBeta
Other point mutations / same position
Reference:	A tale of two tails: cytosolic termini and K(+) channel function. Varshney A, Mathew MK Prog Biophys Mol Biol 2003 Nov;83(3):153-70.	Medline
Other point mutations / same article	List
Text source	HTML full text
Validation status	Not yet checked

Relevant sentences:

T65P

Another mutation at the N-terminal PAS domain (T65P) of the HERG channels has been recently shown to induce mis-trafficking of channels resulting in the long QT syndrome ( [Paulussen et al (2002 ])

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005