KChannelDB: Extraction of mutation data from the literature

2005, KChannelDB.

This data was extracted from Medline abstracts and full texts (when available) in an automated manner.

The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation K262M was found are listed after the table.

The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.

Point mutation K262M in KCAB2_HUMAN

Point mutation:	K262M
Domain:	Not determined
General numbering (KChannelDB):	-
Protein:	KCAB2_HUMAN (KCNAB2,KCNA2B, KCNK)	Swiss-Prot Cross-reference table Family page
Protein isoforms	2
Other point mutations / same protein	List of mutations in KCAB2_HUMAN
Family alignments	Potassium channel beta subunits KvBeta
Other point mutations / same position
Reference:	Binding of pyridine nucleotide coenzymes to the beta-subunit of the voltage-sensitive K+ channel. Liu SQ, Jin H, Zacarias A, Srivastava S, Bhatnagar A J Biol Chem 2001 Apr 13;276(15):11812-20.	Medline
Other point mutations / same article	List
Text source	HTML full text
Validation status	Not yet checked

Relevant sentences:

K262M

The K262M mutation in AR prevents tight binding of NADPH (K m NADPH increases > 60-fold) and leads to an increase in the overall catalytic rate of the enzyme (18 )

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005