This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation F656C was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|General numbering (KChannelDB):||658|
|Protein:||KCNH2_HUMAN (KCNH2,ERG, ERG1, HERG, HERG)||Swiss-Prot|
|Other point mutations / same protein / same position||Point mutations at position 656 in KCNH2_HUMAN|
|Other point mutations / same protein||List of mutations in KCNH2_HUMAN|
eag related KCNH (Kv10-12)|
K+ voltage-gated channels (Kv1-12,Kca2-5)
Potassium channels 6 TMs
|Other point mutations / same position||
Position 656 in eag related KCNH (Kv10-12) family |
Position 644 in K+ voltage-gated channels (Kv1-12,Kca2-5) family
Position 404 in Potassium channels 6 TMs family
|Reference:||Blockade of HERG cardiac K+ current by antifungal drug miconazole.|
Kikuchi K, Nagatomo T, Abe H, Kawakami K, Duff HJ, Makielski JC, January CT, Nakashima Y
Br J Pharmacol 2004 Dec 13;.
|Other point mutations / same article||List|
|Validation status||Not yet checked|