2005, KChannelDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation S601G was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | S601G | |
| Domain: | Loop 5-6 | |
| General numbering (KChannelDB): | - | |
| Protein: | KCNH2_HUMAN (KCNH2,ERG, ERG1, HERG, HERG) | Swiss-Prot Cross-reference table Family page |
| Protein isoforms | 4 | |
| Other point mutations / same protein / same position | Point mutations at position 601 in KCNH2_HUMAN | |
| Other point mutations / same protein | List of mutations in KCNH2_HUMAN | |
| Family alignments |
eag related KCNH (Kv10-12) K+ voltage-gated channels (Kv1-12,Kca2-5) Potassium channels 6 TMs | |
| Other point mutations / same position |
Position 601 in eag related KCNH (Kv10-12) family Position 589 in K+ voltage-gated channels (Kv1-12,Kca2-5) family | |
| Reference: | Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits. Gong Q, Anderson CL, January CT, Zhou Z Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H652-8. Epub 2004 Apr 8. | Medline |
| Other point mutations / same article | List | |
| Text source | HTML full text | |
| Validation status | Not yet checked |
Relevant sentences:
S601G
cmbi.ru.nl), 17-Aug-2005