2005, KChannelDB.
This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation M160L was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
| Point mutation: | M160L | |
| Domain: | TRANSMEM II | |
| General numbering (KChannelDB): | 246 | |
| Protein: | IRK2_RAT (Kcnj2,Irk) | Swiss-Prot Cross-reference table Family page |
| Other point mutations / same protein | List of mutations in IRK2_RAT | |
| Family alignments |
Inward rectifiers (Kir) Potassium channels 2 TMs | |
| Other point mutations / same position |
Position 142 in Inward rectifiers (Kir) family Position 142 in Potassium channels 2 TMs family | |
| Reference: | Regulation of Kir channels by intracellular pH and extracellular K(+): mechanisms of coupling. Dahlmann A, Li M, Gao Z, McGarrigle D, Sackin H, Palmer LG J Gen Physiol 2004 Apr;123(4):441-54. | Medline |
| Other point mutations / same article | List | |
| Text source | HTML full text | |
| Validation status | Not yet checked |
Relevant sentences:
M160L
cmbi.ru.nl), 17-Aug-2005