KChannelDB: Extraction of mutation data from the literature

2005, KChannelDB.

This data was extracted from Medline abstracts and full texts (when available) in an automated manner.

The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation M84K was found are listed after the table.

The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.

Point mutation M84K in KCNE4_HUMAN

Point mutation:	M84K
Domain:	C-term
General numbering (KChannelDB):	-
Protein:	KCNE4_HUMAN (KCNE)	Swiss-Prot Cross-reference table Family page
Other point mutations / same protein	List of mutations in KCNE4_HUMAN
Family alignments	IsK related channels (minK,MiRP,AMMECR2) Potassium channels 1 TM
Other point mutations / same position
Reference:	Molecular mechanism of a COOH-terminal gating determinant in the ROMK channel revealed by a Bartter's disease mutation. Flagg TP, Yoo D, Sciortino CM, Tate M, Romero MF, Welling PA J Physiol 2002 Oct 15;544(Pt 2):351-62.	Medline
Other point mutations / same article	List
Text source	PDF full text
Validation status	Not yet checked

Relevant sentences:

M84K

The reverse mutation , M84K in Kir2.1 , introduced dependence on pHi similar to the wild-type Kir1.1a channel (Fakler et al. 1996)

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005