KChannelDB: Extraction of mutation data from the literature

2005, KChannelDB.

This data was extracted from Medline abstracts and full texts (when available) in an automated manner.

The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation R301A was found are listed after the table.

The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.

Point mutation R301A in IRK11_MOUSE

Point mutation:	R301A
Domain:	C-term
General numbering (KChannelDB):	-
Protein:	IRK11_MOUSE (Kcnj1)	Swiss-Prot Cross-reference table Family page
Other point mutations / same protein / same position	Point mutations at position 301 in IRK11_MOUSE
Other point mutations / same protein	List of mutations in IRK11_MOUSE
Family alignments	Inward rectifiers (Kir) Potassium channels 2 TMs
Other point mutations / same position	Position 294 in Inward rectifiers (Kir) family Position 294 in Potassium channels 2 TMs family
Reference:	Molecular basis for Kir6.2 channel inhibition by adenine nucleotides. Ribalet B, John SA, Weiss JN Biophys J 2003 Jan;84(1):266-76.	Medline
Other point mutations / same article	List
Text source	HTML full text
Validation status	Not yet checked

Relevant sentences:

R301A

However , in their study mutations , R176A , R177A , R192A , R206A , K222A , R301A , and R314A did not yield current in the absence of PIP2 and their sensitivity to ATP could not be assessed

F.Horn (kchanneldbcmbi.ru.nl), 17-Aug-2005