This data was extracted from Medline abstracts and full texts (when available) in an automated manner.
The table below describes the selected point mutation and provides links to other documents. The sentence(s) where the point mutation F137S was found are listed after the table.
The mutated residues are also indicated in the family sequence alignments and hyperlinked to the corresponding mutation pages.
|Cited point mutation:||Phe137Ser,Phe-137|
|General numbering (KChannelDB):||-|
|Protein:||IRK3_RAT (Kcnj3,Girk1, Kg)||Swiss-Prot|
|Other point mutations / same protein / same position||Point mutations at position 137 in IRK3_RAT|
|Other point mutations / same protein||List of mutations in IRK3_RAT|
Inward rectifiers (Kir)|
Potassium channels 2 TMs
|Other point mutations / same position||
Position 118 in Inward rectifiers (Kir) family |
Position 118 in Potassium channels 2 TMs family
|Reference:||Molecular determinants for activation of G-protein-coupled inward rectifier K+ (GIRK) channels by extracellular acidosis.|
Mao J, Li L, McManus M, Wu J, Cui N, Jiang C
J Biol Chem 2002 Nov 29;277(48):46166-71.
|Other point mutations / same article||List|
|Text source||HTML full text|
|Validation status||Not yet checked|